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Caspase 6 antibody (N-Term)

CASP6 Reactivity: Human WB, IHC (p) Host: Rabbit Polyclonal unconjugated
Catalog No. ABIN3043219
  • Target See all Caspase 6 (CASP6) Antibodies
    Caspase 6 (CASP6) (Caspase 6, Apoptosis-Related Cysteine Peptidase (CASP6))
    Binding Specificity
    • 26
    • 16
    • 15
    • 12
    • 11
    • 8
    • 8
    • 8
    • 7
    • 5
    • 4
    • 3
    • 3
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 24-44, N-Term
    Reactivity
    • 138
    • 78
    • 36
    • 11
    • 3
    • 2
    • 1
    • 1
    • 1
    • 1
    Human
    Host
    • 160
    • 10
    • 1
    Rabbit
    Clonality
    • 149
    • 22
    Polyclonal
    Conjugate
    • 76
    • 16
    • 13
    • 9
    • 7
    • 5
    • 5
    • 5
    • 5
    • 5
    • 5
    • 5
    • 3
    • 3
    • 3
    • 3
    • 3
    This Caspase 6 antibody is un-conjugated
    Application
    • 138
    • 68
    • 61
    • 41
    • 40
    • 30
    • 26
    • 17
    • 14
    • 13
    • 11
    • 5
    • 4
    • 3
    • 1
    Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
    Purpose
    Rabbit IgG polyclonal antibody for Caspase-6(CASP6) detection. Tested with WB, IHC-P in Human.
    Sequence
    AFYKREMFDP AEKYKMDHRR R
    Cross-Reactivity (Details)
    No cross reactivity with other proteins.
    Characteristics
    Rabbit IgG polyclonal antibody for Caspase-6(CASP6) detection. Tested with WB, IHC-P in Human.
    Gene Name: caspase 6, apoptosis-related cysteine peptidase
    Protein Name: Caspase-6(CASP-6)
    Purification
    Immunogen affinity purified.
    Immunogen
    A synthetic peptide corresponding to a sequence at the N-terminus of human Caspase-6(P18)(24-44aa AFYKREMFDPAEKYKMDHRRR).
    Isotype
    IgG
    Top Product
    Discover our top product CASP6 Primary Antibody
  • Application Notes
    WB: Concentration: 0.1-0.5 μg/mL, Tested Species: Human
    IHC-P: Concentration: 0.5-1 μg/mL, Tested Species: Human, Epitope Retrieval by Heat: Boiling the paraffin sections in 10 mM citrate buffer, pH 6.0, for 20 mins is required for the staining of formalin/paraffin sections.
    Notes: Tested Species: Species with positive results. Predicted Species: Species predicted to be fit for the product based on sequence similarities. Other applications have not been tested. Optimal dilutions should be determined by end users.
    Comment

    Antibody can be supported by chemiluminescence kit ABIN921124 in WB, supported by ABIN921231 in IHC(P).

    Restrictions
    For Research Use only
  • Format
    Lyophilized
    Reconstitution
    Add 0.2 mL of distilled water will yield a concentration of 500 μg/mL.
    Concentration
    500 μg/mL
    Buffer
    Each vial contains 5 mg BSA, 0.9 mg NaCl, 0.2 mg Na2HPO4, 0.05 mg Thimerosal, 0.05 mg Sodium azide.
    Preservative
    Thimerosal (Merthiolate), Sodium azide
    Precaution of Use
    This product contains Sodium azide and Thimerosal (Merthiolate): POISONOUS AND HAZARDOUS SUBSTANCES which should be handled by trained staff only.
    Handling Advice
    Avoid repeated freezing and thawing.
    Storage
    4 °C/-20 °C
    Storage Comment
    At -20°C for one year. After reconstitution, at 4°C for one month.
    It can also be aliquotted and stored frozen at -20 °C for a longer time. Avoid repeated freezing and thawing.
    Expiry Date
    12 months
  • Target
    Caspase 6 (CASP6) (Caspase 6, Apoptosis-Related Cysteine Peptidase (CASP6))
    Alternative Name
    CASP6 (CASP6 Products)
    Synonyms
    xCaspase-6 antibody, mch2 antibody, caspase-6 antibody, zgc:112960 antibody, CASP6 antibody, casp6 antibody, Mch2 antibody, mCASP-6 antibody, MCH2 antibody, caspase 6 L homeolog antibody, caspase 6 antibody, caspase 6, apoptosis-related cysteine peptidase antibody, group XIIA secretory phospholipase A2 antibody, caspase-6 antibody, casp6.L antibody, casp6 antibody, CASP6 antibody, CpipJ_CPIJ017008 antibody, Casp6 antibody
    Background
    Caspase 6 is an enzyme that in humans is encoded by the caspase 6 gene. This gene encodes a protein that is a member of the cysteine-aspartic acid protease(caspase) family. Using radiation hybrid mapping, the Caspase 6 gene is localized to human chromosome 4q25-q26. Caspase 6 functions as a downstream enzyme in the caspase activation cascade. And Caspase 6 can cleave lamin A to its signature apoptotic fragment.

    Synonyms: Apoptosis Related Cysteine Protease antibody|Apoptotic cysteine protease MCH2 antibody|Apoptotic protease MCH 2 antibody|Apoptotic protease Mch-2 antibody|Apoptotic protease MCH2 antibody|Casp 6 antibody|CASP-6 antibody|Casp6 antibody|Caspase 6 antibody|Caspase 6 apoptosis related cysteine protease antibody|Caspase 6 precursor antibody|Caspase 6, apoptosis related cysteine peptidase antibody|Caspase-6 subunit p18 antibody|Caspase6 antibody|Human cysteine protease Mch2 isoform alpha antibody|Mch 2 antibody|Mch2 antibody|OTTHUMP00000162742 antibody|OTTHUMP00000162743 antibody
    UniProt
    P55212
    Pathways
    Apoptosis, Caspase Cascade in Apoptosis
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