STX1A antibody (N-Term)

Catalog No. ABIN3043303

Product Details anti-STX1A Antibody

Target: STX1A (Syntaxin 1A (Brain) (STX1A))

Binding Specificity: AA 1-28, N-Term

Reactivity: Human, Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This STX1A antibody is un-conjugated

Application: Western Blotting (WB)

Purpose: Rabbit IgG polyclonal antibody for Syntaxin-1A(STX1A) detection. Tested with WB in Human,Mouse,Rat.

Sequence: MKDRTQELRT AKDSDDDDDV AVTVDRDR

Cross-Reactivity (Details): No cross reactivity with other proteins.

Characteristics: Rabbit IgG polyclonal antibody for Syntaxin-1A(STX1A) detection. Tested with WB in Human,Mouse,Rat.
Gene Name: syntaxin 1A (brain)
Protein Name: Syntaxin-1A

Purification: Immunogen affinity purified.

Immunogen: A synthetic peptide corresponding to a sequence at the N-terminus of human Syntaxin 1a(1-28aa MKDRTQELRTAKDSDDDDDVAVTVDRDR), different from the related mouse and rat sequences by one amino acid.

Isotype: IgG

Application Details

Application Notes: WB: Concentration: 0.1-0.5 μg/mL, Tested Species: Human, Mouse, Rat , The detection limit for Syntaxin 1a is approximately 0.1 ng/lane under reducing conditions.
Notes: Tested Species: Species with positive results.
Other applications have not been tested. Optimal dilutions should be determined by end users.

Comment:

Antibody can be supported by chemiluminescence kit ABIN921124 in WB.

Restrictions: For Research Use only

Handling

Format: Lyophilized

Reconstitution: Add 0.2 mL of distilled water will yield a concentration of 500 μg/mL.

Concentration: 500 μg/mL

Buffer: Each vial contains 5 mg BSA, 0.9 mg NaCl, 0.2 mg Na2HPO4, 0.05 mg Sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freezing and thawing.

Storage: 4 °C/-20 °C

Storage Comment: At -20°C for one year. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20 °C for a longer time. Avoid repeated freezing and thawing.

Target Details for STX1A

Target: STX1A (Syntaxin 1A (Brain) (STX1A))

Alternative Name: STX1A (STX1A Products)

Synonyms: HPC-1 antibody, P35-1 antibody, STX1 antibody, SYN1A antibody, STX1A antibody, hpc-1 antibody, p35-1 antibody, stx1 antibody, sx1a antibody, syntaxin1a antibody, CG10716 antibody, CG18615 antibody, CG31136 antibody, CG5448 antibody, CT30033 antibody, Dm Syx1 antibody, DmSyx1A antibody, Dmel\\CG31136 antibody, SYX1A antibody, Syt1A antibody, Syx antibody, Syx-1A antibody, Syx1 antibody, Syx1a antibody, SyxA antibody, anon-EST:Gibbs4 antibody, anon-WO02059370.54 antibody, dSyx1 antibody, l(3)06737 antibody, synt antibody, syt-1A antibody, syx antibody, syx-1 antibody, syx-1A antibody, syx1 antibody, syx1A antibody, syntaxin 1A antibody, syntaxin 1A (brain) antibody, Syntaxin 1A antibody, syntaxin-1A antibody, STX1A antibody, Stx1a antibody, stx1a antibody, Syx1A antibody, EDI_005240 antibody, Tsp_07354 antibody

Background: Syntaxin-1A is a member of the syntaxin superfamily. Syntaxins are nervous system-specific proteins implicated in the docking of synaptic vesicles with the presynaptic plasma membrane. Syntaxins possess a single C-terminal transmembrane domain, a SNARE [Soluble NSF (N-ethylmaleimide-sensitive fusion protein)-Attachment protein REceptor] domain (known as H3), and an N-terminal regulatory domain (Habc). Syntaxins bind synaptotagminin a calcium-dependent fashion and interact with voltage dependent calcium and potassium channels via the C-terminal H3 domain. Syntaxin-1A is a key protein in ion channel regulation and synaptic exocytosis.

Synonyms: EPIM antibody|Epimorphin antibody|EPM antibody|FP17469 antibody|HPC 1 antibody|Neuron specific antigen HPC 1 antibody|Neuron specific antigen HPC1 antibody|neuron-specific antigen HPC 1 antibody|P35 1 antibody|P35 1 antibody|STX 1 antibody|STX 1A antibody|STX1 antibody|STX1 antibody|STX1A antibody|Stx1b antibody|STX1B_HUMAN antibody|STX1B1 antibody|STX1B2 antibody|STX2 antibody|STX2A antibody|STX2B antibody|STX2C antibody|STX3 antibody|STX3A antibody|Syntaxin 1A antibody|Syntaxin 1A brain antibody|Syntaxin 1B antibody|Syntaxin 1B1 antibody|Syntaxin 1B2 antibody|Syntaxin 2 antibody|Syntaxin 3 antibody|Syntaxin 3A antibody|Syntaxin-1B antibody|Syntaxin-1B1 antibody|Syntaxin-1B2 antibody

Gene ID: 6804

UniProt: Q16623

Pathways: Peptide Hormone Metabolism, Synaptic Membrane, Synaptic Vesicle Exocytosis, Dicarboxylic Acid Transport