SYNPO antibody (C-Term)

Catalog No. ABIN3043306

Product Details anti-SYNPO Antibody

Target: SYNPO (Synaptopodin (SYNPO))

Binding Specificity: AA 629-658, C-Term

Reactivity: Human, Mouse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This SYNPO antibody is un-conjugated

Application: Western Blotting (WB)

Purpose: Rabbit IgG polyclonal antibody for Synaptopodin(SYNPO) detection. Tested with WB in Human,Mouse.

Sequence: EKPKVTPNPD LLDLVQTADE KRRQRDQGEV

Cross-Reactivity (Details): No cross reactivity with other proteins.

Characteristics: Rabbit IgG polyclonal antibody for Synaptopodin(SYNPO) detection. Tested with WB in Human,Mouse.
Gene Name: synaptopodin
Protein Name: Synaptopodin

Purification: Immunogen affinity purified.

Immunogen: A synthetic peptide corresponding to a sequence at the C-terminus of human Synaptopodin(629-658aa EKPKVTPNPDLLDLVQTADEKRRQRDQGEV), different from the related mouse sequence by one amino acid, and identical to the related rat sequence.

Isotype: IgG

Application Details

Application Notes: WB: Concentration: 0.1-0.5 μg/mL, Tested Species:Human, Mouse, The detection limit for Synaptopodin is approximately 0.1 ng/lane under reducing conditions.
Notes: Tested Species: Species with positive results.
Other applications have not been tested. Optimal dilutions should be determined by end users.

Comment:

Antibody can be supported by chemiluminescence kit ABIN921124 in WB.

Restrictions: For Research Use only

Handling

Format: Lyophilized

Reconstitution: Add 0.2 mL of distilled water will yield a concentration of 500 μg/mL.

Concentration: 500 μg/mL

Buffer: Each vial contains 5 mg BSA, 0.9 mg NaCl, 0.2 mg Na2HPO4, 0.05 mg Sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freezing and thawing.

Storage: 4 °C/-20 °C

Storage Comment: At -20°C for one year. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20 °C for a longer time. Avoid repeated freezing and thawing.

Target Details for SYNPO

Target: SYNPO (Synaptopodin (SYNPO))

Alternative Name: SYNPO (SYNPO Products)

Synonyms: SYNPO antibody, DKFZp459N012 antibody, 9030217H17Rik antibody, 9130229N11 antibody, 9330140I15Rik antibody, AW046661 antibody, synaptopodin antibody, formin-like protein 5 antibody, SYNPO antibody, LOC100147046 antibody, Synpo antibody

Background: Synaptopodin is also known as SYNPO. The spine apparatus (SA) is a specialized form of endoplasmic reticulum (ER) that is found in a subpopulation of dendritic spines in central neurons. The SA consists of a series of stacked discs that are thought to be connected to each other and to the dendritic system of ER-tubules. The actin binding protein synaptopodin (which has originally been described in podocytes of the kidney) is an essential component of the SA. Mice that lack the gene for synaptopodin do not form a spine apparatus. The SA is believed to play a critical role in learning and memory. In summary, an important function of the spine apparatus is the regulation of plasticity at individual synapses, a process known as metaplasticity. The International Radiation Hybrid Mapping Consortium mapped the SYNPO gene to chromosome 5.

Synonyms: KIAA1029 antibody|Synaptopodin antibody|SYNPO antibody|SYNPO_HUMAN antibody

Gene ID: 11346

UniProt: Q8N3V7