LOXL2 antibody (C-Term)

Catalog No. ABIN3043464

Product Details anti-LOXL2 Antibody

Target: LOXL2 (Lysyl Oxidase-Like 2 (LOXL2))

Binding Specificity: AA 739-770, C-Term

Reactivity: Human, Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This LOXL2 antibody is un-conjugated

Application: Western Blotting (WB)

Purpose: Rabbit IgG polyclonal antibody for Lysyl oxidase homolog 2(LOXL2) detection. Tested with WB in Human,Mouse,Rat.

Sequence: HRIWMYNCHI GGSFSEETEK KFEHFSGLLN NQ

Cross-Reactivity (Details): No cross reactivity with other proteins.

Characteristics: Rabbit IgG polyclonal antibody for Lysyl oxidase homolog 2(LOXL2) detection. Tested with WB in Human,Mouse,Rat.
Gene Name: lysyl oxidase-like 2
Protein Name: Lysyl oxidase homolog 2

Purification: Immunogen affinity purified.

Immunogen: A synthetic peptide corresponding to a sequence at the C-terminus of human LOXL2 (739-770aa HRIWMYNCHIGGSFSEETEKKFEHFSGLLNNQ), different from the related mouse and rat sequences by four amino acids.

Isotype: IgG

Application Details

Application Notes: WB: Concentration: 0.1-0.5 μg/mL, Tested Species: Human, Mouse, Rat
Notes: Tested Species: Species with positive results.
Other applications have not been tested. Optimal dilutions should be determined by end users.

Comment:

Antibody can be supported by chemiluminescence kit ABIN921124 in WB.

Restrictions: For Research Use only

Handling

Format: Lyophilized

Reconstitution: Add 0.2 mL of distilled water will yield a concentration of 500 μg/mL.

Concentration: 500 μg/mL

Buffer: Each vial contains 5 mg BSA, 0.9 mg NaCl, 0.2 mg Na2HPO4, 0.05 mg Sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freezing and thawing.

Storage: 4 °C/-20 °C

Storage Comment: At -20°C for one year. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20 °C for a longer time. Avoid repeated freezing and thawing.

Target Details for LOXL2

Target: LOXL2 (Lysyl Oxidase-Like 2 (LOXL2))

Alternative Name: LOXL2 (LOXL2 Products)

Synonyms: LOR2 antibody, WS9-14 antibody, CG4402 antibody, Dmel\\CG4402 antibody, Dmloxl-2 antibody, dmlox-2 antibody, 1110004B06Rik antibody, 4930526G11Rik antibody, 9430067E15Rik antibody, GB13360 antibody, lox2-like antibody, LOXL2 antibody, lor2 antibody, loxl-2 antibody, ws9-14 antibody, im:7136137 antibody, si:dkeyp-32b1.1 antibody, wu:fk12g04 antibody, zgc:158414 antibody, lysyl oxidase like 2 antibody, lysyl oxidase-like 2 antibody, lysyl oxidase homolog 4 antibody, lysyl oxidase like 2 L homeolog antibody, lysyl oxidase-like 2b antibody, LOXL2 antibody, lox2 antibody, Loxl2 antibody, LOC408544 antibody, loxl2.L antibody, loxl2 antibody, loxl2b antibody

Background: Lysyl oxidase homolog 2 is an enzyme that in humans is encoded by the LOXL2 gene. This gene encodes a member of the lysyl oxidase gene family. The prototypic member of the family is essential to the biogenesis of connective tissue, encoding an extracellular copper-dependent amine oxidase that catalyses the first step in the formation of crosslinks in collagens and elastin. A highly conserved amino acid sequence at the C-terminus end appears to be sufficient for amine oxidase activity, suggesting that each family member may retain this function. The N-terminus is poorly conserved and may impart additional roles in developmental regulation, senescence, tumor suppression, cell growth control, and chemotaxis to each member of the family. LOXL2 can also crosslink collagen type IV and hence influence the sprouting of new blood vessels.

Synonyms: LOR 2 antibody|LOR2 antibody|LOX L2 antibody|LOXL 2 antibody|LOXL2 antibody|LOXL2_HUMAN antibody|Lysyl oxidase homolog 2 antibody| Lysyl oxidase like 2 antibody|Lysyl oxidase like protein 2 antibody|Lysyl oxidase related 2 antibody|Lysyl oxidase related protein 2 antibody|Lysyl oxidase related protein WS9 14 antibody|Lysyl oxidase-like protein 2 antibody|Lysyl oxidase-related protein 2 antibody| Lysyl oxidase-related protein WS9-14 antibody|WS9 14 antibody

Gene ID: 4017

UniProt: Q9Y4K0

Pathways: Chromatin Binding