CCL4 antibody (AA 24-92)

Catalog No. ABIN3043476

Product Details anti-CCL4 Antibody

Target: CCL4 (Chemokine (C-C Motif) Ligand 4 (CCL4))

Binding Specificity: AA 24-92

Reactivity: Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This CCL4 antibody is un-conjugated

Application: Western Blotting (WB)

Purpose: Rabbit IgG polyclonal antibody for C-C motif chemokine 4(CCL4) detection. Tested with WB in Rat.

Cross-Reactivity (Details): No cross reactivity with other proteins.

Characteristics: Rabbit IgG polyclonal antibody for C-C motif chemokine 4(CCL4) detection. Tested with WB in Rat.
Gene Name: chemokine (C-C motif) ligand 4
Protein Name: C-C motif chemokine 4

Purification: Immunogen affinity purified.

Immunogen: E.coli-derived rat CCL4 recombinant protein (Position: A24-N92). Rat CCL4 shares 80% and 86% amino acid (aa) sequences identity with human and mouse CCL4, respectively.

Isotype: IgG

Application Details

Application Notes: WB: Concentration: 0.1-0.5 μg/mL, Tested Species: Rat, The detection limit for CCL4 is approximately 0.25 ng/lane under reducing conditions.
Notes: Tested Species: Species with positive results.
Other applications have not been tested. Optimal dilutions should be determined by end users.

Comment:

Antibody can be supported by chemiluminescence kit ABIN921124 in WB.

Restrictions: For Research Use only

Handling

Format: Lyophilized

Reconstitution: Add 0.2 mL of distilled water will yield a concentration of 500 μg/mL.

Concentration: 500 μg/mL

Buffer: Each vial contains 5 mg BSA, 0.9 mg NaCl, 0.2 mg Na2HPO4, 0.05 mg Sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freezing and thawing.

Storage: 4 °C/-20 °C

Storage Comment: At -20°C for one year. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20 °C for a longer time. Avoid repeated freezing and thawing.

Target Details for CCL4

Target: CCL4 (Chemokine (C-C Motif) Ligand 4 (CCL4))

Alternative Name: CCL4 (CCL4 Products)

Synonyms: ACT2 antibody, AT744.1 antibody, G-26 antibody, HC21 antibody, LAG-1 antibody, LAG1 antibody, MIP-1-beta antibody, MIP1B antibody, MIP1B1 antibody, SCYA2 antibody, SCYA4 antibody, CCL4 antibody, K203 antibody, Mip1-b antibody, Scya4 antibody, MIP-1beta antibody, MIP-1BETA antibody, MIP1b antibody, SCY4A antibody, Act-2 antibody, MIP-1B antibody, Mip1b antibody, ACT-2 antibody, AT744.2 antibody, CCL4L antibody, SCYA4L antibody, SCYA4L1 antibody, SCYA4L2 antibody, C-C motif chemokine ligand 4 antibody, chemokine (C-C motif) ligand 4 antibody, chemokine (C-C motif) ligand 4-like 1 antibody, C-C motif chemokine ligand 4 like 1 antibody, CCL4 antibody, Ccl4 antibody, CCL4L1 antibody

Background: Chemokine(C-C motif) ligand 4, also known as CCL4, is a protein which in human is encoded by the CCL4 gene. By analysis of somatic cell hybrids and by in situ hybridization, the CCL4 gene was assigned to 17q21-q23. It is a CC chemokine with specificity for CCR5 receptors. It is a chemoattractant for natural killer cells, monocytes and a variety of other immune cells. CCL4 is a major HIV-suppressive factor produced by CD8+ T cells. Performing-low memory CD8+ T cells that normally synthesize CCL4. Based on functional analysis of CCL4, one or more additional beta chemokine receptors that transduce CCL4 signals must also exist. MIP-1alpha and CCL4 have been shown to lack affinity for the erythrocyte surface chemokine receptor/Duffy antigen that binds many alpha as well as beta chemokines(11, 14).

Synonyms: MIP 1 beta antibody|Secreted protein G 26 antibody|ACT 2 antibody|ACT-2 antibody|ACT2 antibody|AT744.1 antibody|AT744.2 antibody|C C motif chemokine 4 antibody|C C motif chemokine 4 like antibody|CC chemokine ligand 4 antibody|CC chemokine ligand 4L1d2 antibody|CC chemokine ligand 4L2 antibody|CCL4 antibody|CCL4_HUMAN antibody|ccl4l 1 antibody|CCL4L antibody|CCL4L1 antibody|Chemokine (C C motif) ligand 4 antibody|Chemokine (C C motif) ligand 4 like 1 antibody|Chemokine (C C motif) ligand 4 like 1, telomeric antibody|Chemokine (C C motif) ligand 4 like 2 antibody|Chemokine CC Motif Ligand 4 antibody|G 26 antibody|G 26 T lymphocyte secreted protein antibody|G-26 T-lymphocyte-secreted protein antibody|HC21 antibody|LAG 1 antibody|LAG-1 antibody|LAG1 antibody|Lymphocyte activation gene 1 antibody|Lymphocyte activation gene 1 protein antibody|Macrophage inflammatory protein 1 beta antibody|Macrophage inflammatory protein 1-beta antibody|Macrophage inflammatory protein 1b2 antibody|MGC104418 antibody|MGC126025 antibody|MGC126026 antibody|MIP 1 beta antibody|MIP-1-beta antibody|MIP-1-beta(1-69) antibody|MIP-1-beta(3-69) antibody|MIP1 beta antibody|MIP1B antibody|MIP1B1 antibody|Monocyte adherence induced protein 5 alpha antibody|PAT 744 antibody|Protein H400 antibody|SCYA2 antibody|SCYA4 antibody|SCYA4L antibody|Secreted protein G 26 antibody|Secreted protein G26 antibody|SIS gamma antibody|SIS-gamma antibody|Small inducible cytokine A4 (homologous to mouse Mip 1b) antibody|Small inducible cytokine A4 antibody|Small-inducible cytokine A4 antibody|T cell activation protein 2 antibody|T-cell activation protein 2 antibody

Gene ID: 116637

UniProt: P50230