CCL7 antibody (AA 24-97)

Catalog No. ABIN3043479

Product Details anti-CCL7 Antibody

Target: CCL7 (Chemokine (C-C Motif) Ligand 7 (CCL7))

Binding Specificity: AA 24-97

Reactivity: Mouse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This CCL7 antibody is un-conjugated

Application: Western Blotting (WB), ELISA

Purpose: Rabbit IgG polyclonal antibody for C-C motif chemokine 7(CCL7) detection. Tested with WB, ELISA in Mouse.

Cross-Reactivity (Details): No cross reactivity with other proteins.

Characteristics: Rabbit IgG polyclonal antibody for C-C motif chemokine 7(CCL7) detection. Tested with WB, ELISA in Mouse.
Gene Name: chemokine (C-C motif) ligand 7
Protein Name: C-C motif chemokine 7

Purification: Immunogen affinity purified.

Immunogen: E.coli-derived mouse MCP3 recombinant protein (Position: Q24-P97). Mouse MCP3 shares 60% and 95% amino acid (aa) sequences identity with human and rat MCP3, respectively.

Isotype: IgG

Application Details

Application Notes: WB: Concentration: 0.1-0.5 μg/mL, Tested Species: Mouse, The detection limit for MCP3 is approximately 0.25 ng/lane under reducing conditions.
ELISA: Concentration: 0.1-0.5 μg/mL, Tested Species: Mouse

Notes: Tested Species: Species with positive results.
Other applications have not been tested. Optimal dilutions should be determined by end users.

Comment:

Antibody can be supported by chemiluminescence kit ABIN921124 in WB.

Restrictions: For Research Use only

Handling

Format: Lyophilized

Reconstitution: Add 0.2 mL of distilled water will yield a concentration of 500 μg/mL.

Concentration: 500 μg/mL

Buffer: Each vial contains 5 mg BSA, 0.9 mg NaCl, 0.2 mg Na2HPO4, 0.05 mg Sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freezing and thawing.

Storage: 4 °C/-20 °C

Storage Comment: At -20°C for one year. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20 °C for a longer time. Avoid repeated freezing and thawing.

Target Details for CCL7

Target: CCL7 (Chemokine (C-C Motif) Ligand 7 (CCL7))

Alternative Name: CCL7 (CCL7 Products)

Synonyms: CCL7 antibody, FIC antibody, MARC antibody, MCP-3 antibody, MCP3 antibody, NC28 antibody, SCYA6 antibody, SCYA7 antibody, Scya7 antibody, fic antibody, marc antibody, mcp3 antibody, C-C motif chemokine ligand 7 antibody, chemokine (C-C motif) ligand 7 antibody, CCL7 antibody, Ccl7 antibody

Background: Chemokine (C-C motif) ligand 7 (CCL7) is a small cytokine known as a chemokine that was previously called monocyte-specific chemokine 3 (MCP3). It belongs to the C-C chemokine family. By fluorescence in situ hybridization, MCP3 gene is mapped to chromosome 17q11.2-q12. MCP3 was identified as a physiologic substrate of gelatinase A. Cleaved MCP3 binds to CC-chemokine receptors-1, -2, and -3, but no longer induces calcium fluxes or promotes chemotaxis, and instead acts as a general chemokine antagonist that dampens inflammation, it has been found that matrix metalloproteinases are both effectors and regulators of the inflammatory response.

Synonyms: C-C motif chemokine 7 antibody|CCL7 antibody|CCL7_HUMAN antibody|Chemokine CC Motif Ligand 7 antibody|FIC antibody|MARC antibody|MCP-3 antibody|MCP3 antibody|Monocyte chemoattractant protein 3 antibody|Monocyte chemotactic protein 3 antibody|NC28 antibody|RP23-350G1.4 antibody|SCYA6 antibody|SCYA7 antibody|Small inducible cytokine A7 antibody|Small-inducible cytokine A7 antibody

Gene ID: 20306

UniProt: Q03366