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Claudin 5 antibody (C-Term)

CLDN5 Reactivity: Rat WB Host: Rabbit Polyclonal unconjugated
Catalog No. ABIN3043521
  • Target See all Claudin 5 (CLDN5) Antibodies
    Claudin 5 (CLDN5)
    Binding Specificity
    • 10
    • 7
    • 5
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 191-218, C-Term
    Reactivity
    • 60
    • 39
    • 36
    • 18
    • 17
    • 14
    • 3
    • 1
    • 1
    • 1
    Rat
    Host
    • 56
    • 6
    Rabbit
    Clonality
    • 49
    • 13
    Polyclonal
    Conjugate
    • 32
    • 4
    • 3
    • 3
    • 3
    • 3
    • 3
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    This Claudin 5 antibody is un-conjugated
    Application
    • 33
    • 20
    • 18
    • 13
    • 6
    • 6
    • 3
    • 1
    • 1
    Western Blotting (WB)
    Purpose
    Rabbit IgG polyclonal antibody for Claudin-5(CLDN5) detection. Tested with WB in Human,Rat.
    Sequence
    RPDLSFPVKY SAPRRPTATG DYDKKNYV
    Cross-Reactivity (Details)
    Predicted Cross Reactivity: human
    No cross reactivity with other proteins.
    Predicted Cross Reactivity: Species predicted to be fit for the product based on sequence similarities.
    Characteristics
    Rabbit IgG polyclonal antibody for Claudin-5(CLDN5) detection. Tested with WB in Human,Rat.
    Gene Name: claudin 5
    Protein Name: Claudin-5
    Purification
    Immunogen affinity purified.
    Immunogen
    A synthetic peptide corresponding to a sequence at the C-terminus of human Claudin 5(191-218aa RPDLSFPVKYSAPRRPTATGDYDKKNYV), different from the related mouse sequence by three amino acids and from the related rat sequence by four amino acids.
    Isotype
    IgG
    Top Product
    Discover our top product CLDN5 Primary Antibody
  • Application Notes
    WB: Concentration: 0.1-0.5 μg/mL, Tested Species: Rat, Predicted Species: Human, The detection limit for Claudin 5 is approximately 0.2 ng/lane under reducing conditions.
    Notes: Tested Species: Species with positive results. Predicted Species: Species predicted to be fit for the product based on sequence similarities.
    Other applications have not been tested. Optimal dilutions should be determined by end users.
    Comment

    Antibody can be supported by chemiluminescence kit ABIN921124 in WB.

    Restrictions
    For Research Use only
  • Format
    Lyophilized
    Reconstitution
    Add 0.2 mL of distilled water will yield a concentration of 500 μg/mL.
    Concentration
    500 μg/mL
    Buffer
    Each vial contains 5 mg BSA, 0.9 mg NaCl, 0.2 mg Na2HPO4, 0.05 mg Thimerosal, 0.05 mg Sodium azide.
    Preservative
    Thimerosal (Merthiolate), Sodium azide
    Precaution of Use
    This product contains Sodium azide and Thimerosal (Merthiolate): POISONOUS AND HAZARDOUS SUBSTANCES which should be handled by trained staff only.
    Handling Advice
    Avoid repeated freezing and thawing.
    Storage
    4 °C/-20 °C
    Storage Comment
    At -20°C for one year. After reconstitution, at 4°C for one month.
    It can also be aliquotted and stored frozen at -20 °C for a longer time. Avoid repeated freezing and thawing.
  • Cen, Liu, Li, He, Wang, Liu, Liu, Ji: "Alteration in P-glycoprotein at the blood-brain barrier in the early period of MCAO in rats." in: The Journal of pharmacy and pharmacology, Vol. 65, Issue 5, pp. 665-72, (2013) (PubMed).

  • Target
    Claudin 5 (CLDN5)
    Alternative Name
    CLDN5 (CLDN5 Products)
    Synonyms
    AWAL antibody, BEC1 antibody, CPETRL1 antibody, TMVCF antibody, cld5 antibody, awal antibody, bec1 antibody, claudin-5 antibody, cpetrl1 antibody, tmvcf antibody, AI854493 antibody, MBEC1 antibody, Tmvcf antibody, cldn5 antibody, zgc:85723 antibody, zgc:103419 antibody, claudin 5 antibody, Claudin-5 antibody, claudin 5 (transmembrane protein deleted in velocardiofacial syndrome) antibody, claudin 5a antibody, claudin 5b antibody, claudin 5 (transmembrane protein deleted in velocardiofacial syndrome) L homeolog antibody, CLDN5 antibody, cld5 antibody, cldn5 antibody, Cldn5 antibody, cldn5a antibody, cldn5b antibody, cldn5.L antibody
    Background
    Claudin-5(CLDN5) also known as BEC1, is a protein that in humans is encoded by the CLDN5 gene. By use of yeast artificial chromosomes, Claudin-5 is localized between polymorphic markers D22S944 and D22S941 on chromosome 22q11, both of which are deleted in more than 80 % of VCFS patients. This gene encodes a member of the claudin family. Claudins are integral membrane proteins and components of tight junction strands. Tight junction strands serve as a physical barrier to prevent solutes and water from passing freely through the paracellular space between epithelial or endothelial cell sheets. What's more, it plays a major role in tight junction-specific obliteration of the intercellular space.

    Synonyms: Androgen withdrawal and apoptosis induced protein RVP1 like antibody|AWAL antibody|BEC 1 antibody|BEC1 antibody|Claudin 5 (transmembrane protein deleted in velocardiofacial syndrome) antibody|Claudin-5 antibody|Claudin5 antibody|CLD5_HUMAN antibody|CLDN 5 antibody|CLDN5 antibody|CPETR L1 antibody|CPETRL 1 antibody|CPETRL1 antibody|TMDVCF antibody|TMVCF antibody|Transmembrane protein deleted in VCFS antibody|Transmembrane protein deleted in velocardiofacial syndrome antibody
    Gene ID
    7122
    UniProt
    O00501
    Pathways
    Hepatitis C
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