NPPA antibody (C-Term)

Catalog No. ABIN3043573

Product Details anti-NPPA Antibody

Target: NPPA (Natriuretic Peptide A (NPPA))

Binding Specificity: AA 124-151, C-Term

Reactivity: Rat, Mouse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This NPPA antibody is un-conjugated

Application: Western Blotting (WB)

Purpose: Rabbit IgG polyclonal antibody for Natriuretic peptides A(NPPA) detection. Tested with WB in Human,Mouse,Rat.

Sequence: SLRRSSCFGG RMDRIGAQSG LGCNSFRY

Cross-Reactivity (Details): Predicted Cross Reactivity: human
No cross reactivity with other proteins.
Predicted Cross Reactivity: Species predicted to be fit for the product based on sequence similarities.

Characteristics: Rabbit IgG polyclonal antibody for Natriuretic peptides A(NPPA) detection. Tested with WB in Human,Mouse,Rat.
Gene Name: natriuretic peptide A
Protein Name: Natriuretic peptides A

Purification: Immunogen affinity purified.

Immunogen: A synthetic peptide corresponding to a sequence at the C-terminus of human ANP(124-151aa SLRRSSCFGGRMDRIGAQSGLGCNSFRY), different from the related mouse and rat sequences by one amino acid.

Isotype: IgG

Application Details

Application Notes: WB: Concentration: 0.1-0.5 μg/mL, Tested Species: Mouse, Rat, Predicted Species: Human, The detection limit for ANP is approximately 0.25 ng/lane under reducing conditions.
Notes: Tested Species: Species with positive results. Predicted Species: Species predicted to be fit for the product based on sequence similarities.
Other applications have not been tested. Optimal dilutions should be determined by end users.

Comment:

Antibody can be supported by chemiluminescence kit ABIN921124 in WB.

Restrictions: For Research Use only

Handling

Format: Lyophilized

Reconstitution: Add 0.2 mL of distilled water will yield a concentration of 500 μg/mL.

Concentration: 500 μg/mL

Buffer: Each vial contains 5 mg BSA, 0.9 mg NaCl, 0.2 mg Na2HPO4, 0.05 mg Sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freezing and thawing.

Storage: 4 °C/-20 °C

Storage Comment: At -20°C for one year. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20 °C for a longer time. Avoid repeated freezing and thawing.

Target Details for NPPA

Target: NPPA (Natriuretic Peptide A (NPPA))

Alternative Name: NPPA (NPPA Products)

Synonyms: anp antibody, ANF antibody, ANP antibody, Pnd antibody, RATANF antibody, ATFB6 antibody, CDD-ANF antibody, PND antibody, NPPA antibody, Anf antibody, atrial natriuretic peptide antibody, natriuretic peptide A antibody, natriuretic peptide type A antibody, anp antibody, nppa antibody, NPPA antibody, Nppa antibody

Background: Atrial natriuretic peptide (ANP), also known as NPPA or PND, is a powerful vasodilator, and a protein (polypeptide) hormone secreted by heart muscle cells. This gene is mapped to 1p36.22. It is involved in the homeostatic control of body water, sodium, potassium and fat (adipose tissue). ANP is released by muscle cells in the upper chambers (atria) of the heart (atrial myocytes) in response to high blood volume. It acts to reduce the water, sodium and adipose loads on the circulatory system, thereby reducing blood pressure. ANP has exactly the opposite function of the aldosterone secreted by the zona glomerulosa in regard to its effect on sodium in the kidney - that is, aldosterone stimulates sodium retention and it generates sodium loss.

Synonyms: ANF antibody|ANF_HUMAN antibody|ANP antibody|ATFB6 antibody|Atrial natriuretic factor antibody|Atrial natriuretic factor precursor antibody|Atrial natriuretic peptide antibody|Atriopeptin antibody|Cardionatrin antibody|CDD ANF antibody|CDD-ANF antibody|CDP antibody|Natriuretic peptide A antibody|Natriuretic Peptide Precursor A antibody|NPPA antibody|PND antibody|Prepronatriodilatin antibody

Gene ID: 4878

UniProt: P01160