MAD2L1 antibody (MAD2 Mitotic Arrest Deficient-Like 1 (Yeast)) (AA 2-205)

Details for Product anti-MAD2L1 Antibody No. ABIN3043608, Supplier: Log in to see
Antigen
  • cb408
  • zgc:112133
  • MAD2L1
  • mad2
  • XMad2
  • AA673185
  • MAD2
  • HSMAD2
  • MAD2 mitotic arrest deficient-like 1 (yeast)
  • MAD2 mitotic arrest deficient-like 1
  • MAD2L1
  • mad2l1
  • LOC100218172
  • Mad2l1
Epitope
AA 2-205
19
8
7
6
4
4
4
3
3
2
2
2
1
1
1
1
1
1
Reactivity
Human
120
36
33
9
6
5
4
4
4
3
3
2
2
1
Host
Rabbit
71
34
15
1
Clonality
Polyclonal
Conjugate
This MAD2L1 antibody is un-conjugated
3
3
3
2
2
2
1
1
1
1
1
1
1
1
1
1
1
Application
Western Blotting (WB)
102
46
23
22
21
20
13
6
2
1
1
1
1
1
Options
Supplier
Log in to see
Supplier Product No.
Log in to see
Request

Get this product for free

It's quick and easy to submit your validation proposal. I want to validate this product

Learn more

Available images

Purpose Rabbit IgG polyclonal antibody for Mitotic spindle assembly checkpoint protein MAD2A(MAD2L1) detection. Tested with WB in Human.
Immunogen E.coli-derived human Mad2L1 recombinant protein (Position: A2-D205). Human Mad2L1 shares 94% amino acid (aa) sequence identity with mouse Mad2L1.
Isotype IgG
Cross-Reactivity (Details) No cross reactivity with other proteins.
Characteristics Rabbit IgG polyclonal antibody for Mitotic spindle assembly checkpoint protein MAD2A(MAD2L1) detection. Tested with WB in Human.
Gene Name: MAD2 mitotic arrest deficient-like 1 (yeast)
Protein Name: Mitotic spindle assembly checkpoint protein MAD2A
Purification Immunogen affinity purified.
Alternative Name MAD2L1 (MAD2L1 Antibody Abstract)
Background Mitotic spindle assembly checkpoint protein MAD2A is a protein that in humans is encoded by the MAD2L1 gene. This gene belongs to the MAD2 family. It is mapped to 4q27. MAD2L1 is a component of the mitotic spindle assembly checkpoint that prevents the onset of anaphase until all chromosomes are properly aligned at the metaphase plate. The protein has two highly different native conformations, an inactive open conformation that cannot bind CDC20 and that predominates in cytosolic monomers, and an active closed conformation. It is required for the execution of the mitotic checkpoint which monitors the process of kinetochore-spindle attachment.

Synonyms: Homolog of MAD2 S cerevisiae antibody|HsMAD 2 antibody|HsMAD2 antibody|Human mitotic feedback control protein Madp2 antibody|MAD 2 antibody|MAD 2A antibody|MAD2 antibody|MAD2 like 1 antibody|MAD2 like protein 1 antibody|MAD2 mitotic arrest deficient like 1 antibody|MAD2-like protein 1 antibody|MAD2A antibody|Mad2l1 antibody|MD2L1_HUMAN antibody|Mitotic arrest deficient 2-like protein 1 antibody|Mitotic arrest deficient like 1 antibody|Mitotic arrest deficient yeast homolog antibody|Mitotic arrest deficient yeast homolog like 1 antibody|Mitotic spindle assembly checkpoint protein antibody|Mitotic spindle assembly checkpoint protein MAD2A antibody
Gene ID 4085
UniProt Q13257
Research Area Cell Cycle
Application Notes WB: Concentration: 0.1-0.5 μg/mL, Tested Species: Human, The detection limit for Mad2L1 is approximately 0.5 ng/lane under reducing conditions.
Notes: Tested Species: Species with positive results.
Other applications have not been tested. Optimal dilutions should be determined by end users.
Comment

Antibody can be supported by chemiluminescence kit ABIN921124 in WB.

Restrictions For Research Use only
Format Lyophilized
Reconstitution Add 0.2 mL of distilled water will yield a concentration of 500 μg/mL.
Concentration 500 μg/mL
Buffer Each vial contains 5 mg BSA, 0.9 mg NaCl, 0.2 mg Na2HPO4, 0.05 mg Sodium azide.
Preservative Sodium azide
Precaution of Use This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Handling Advice Avoid repeated freezing and thawing.
Storage 4 °C/-20 °C
Storage Comment At -20°C for one year. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20 °C for a longer time. Avoid repeated freezing and thawing.
Supplier Images
Western Blotting (WB) image for anti-MAD2L1 antibody (MAD2 Mitotic Arrest Deficient-Like 1 (Yeast)) (AA 2-205) (ABIN3043608) Anti- Mad2L1 Picoband antibody, Western blotting All lanes: Anti Mad2L1 at 0.5ug/ml ...