CYP2U1 antibody (C-Term)

Catalog No. ABIN3044054

Product Details anti-CYP2U1 Antibody

Target: CYP2U1 (Cytochrome P450, Family 2, Subfamily U, Polypeptide 1 (CYP2U1))

Binding Specificity: AA 457-473, C-Term

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This CYP2U1 antibody is un-conjugated

Application: Western Blotting (WB), Immunocytochemistry (ICC), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Purpose: Rabbit IgG polyclonal antibody for Cytochrome P450 2U1(CYP2U1) detection. Tested with WB, IHC-P, ICC in Human.

Sequence: EKPEDFYPNR FLDDQGQ

Cross-Reactivity (Details): No cross reactivity with other proteins.

Characteristics: Rabbit IgG polyclonal antibody for Cytochrome P450 2U1(CYP2U1) detection. Tested with WB, IHC-P, ICC in Human.
Gene Name: cytochrome P450, family 2, subfamily U, polypeptide 1
Protein Name: Cytochrome P450 2U1

Purification: Immunogen affinity purified.

Immunogen: A synthetic peptide corresponding to a sequence at the C-terminus of human CYP2U1(457-473aa EKPEDFYPNRFLDDQGQ).

Isotype: IgG

Application Details

Application Notes: WB: Concentration: 0.1-0.5 μg/mL, Tested Species: Human
IHC-P: Concentration: 0.5-1 μg/mL, Tested Species: Human, Epitope Retrieval by Heat: Boiling the paraffin sections in 10 mM citrate buffer, pH 6.0, for 20 mins is required for the staining of formalin/paraffin sections.
ICC: Concentration: 0.5-1 μg/mL, Tested Species: Human
Notes: Tested Species: Species with positive results. Predicted Species: Species predicted to be fit for the product based on sequence similarities. Other applications have not been tested. Optimal dilutions should be determined by end users.

Comment:

Antibody can be supported by chemiluminescence kit ABIN921124 in WB, supported by ABIN921231 in IHC(P) and ICC.

Restrictions: For Research Use only

Handling

Format: Lyophilized

Reconstitution: Add 0.2 mL of distilled water will yield a concentration of 500 μg/mL.

Concentration: 500 μg/mL

Buffer: Each vial contains 5 mg BSA, 0.9 mg NaCl, 0.2 mg Na2HPO4, 0.05 mg Thimerosal, 0.05 mg Sodium azide.

Preservative: Thimerosal (Merthiolate), Sodium azide

Precaution of Use: This product contains Sodium azide and Thimerosal (Merthiolate): POISONOUS AND HAZARDOUS SUBSTANCES which should be handled by trained staff only.

Handling Advice: Avoid repeated freezing and thawing.

Storage: 4 °C/-20 °C

Storage Comment: At -20°C for one year. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20 °C for a longer time. Avoid repeated freezing and thawing.

Expiry Date: 12 months

Target Details for CYP2U1

Target: CYP2U1 (Cytochrome P450, Family 2, Subfamily U, Polypeptide 1 (CYP2U1))

Alternative Name: CYP2U1 (CYP2U1 Products)

Background: CYP2U1(Cytochrome P450, Family 2, Subfamily U, Polypeptide 1), is a protein that in humans is encoded by the CYP2U1 gene. Members of the P450 enzyme family have roles in the tissue-specific conversion of substrates into locally active hormones, vitamins, and signaling molecules, including arachidonic acid derivatives known as eicosanoids. The International Radiation Hybrid Mapping Consortium mapped the CYP2U1 gene to chromosome 4.Chuang et al.(2004) stated that CYP2U1 maps to 4q25. Using recombination experiments in Sf9 insect cells, Chuang et al.(2004) found that CYP2U1 metabolized arachidonic acid, docosahexaenoic acid(DHA), and other long chain fatty acids. Chuang et al.(2004) suggested that CYP2U1 may play a role in brain and immune functions.

Synonyms: CP2U1_HUMAN antibody|CYP2U 1 antibody|CYP2U1 antibody|Cytochrome P450 2U1 antibody|Cytochrome P450, family 2, subfamily U, polypeptide 1 antibody|EC 1.14.14.1 antibody|P450TEC antibody

UniProt: Q7Z449