Coxsackie Adenovirus Receptor antibody (C-Term)

Catalog No. ABIN3044083

Product Details anti-Coxsackie Adenovirus Receptor Antibody

Target: Coxsackie Adenovirus Receptor (CXADR) (Coxsackie Virus and Adenovirus Receptor (CXADR))

Binding Specificity: AA 313-328, C-Term

Reactivity: Human, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This Coxsackie Adenovirus Receptor antibody is un-conjugated

Application: Western Blotting (WB)

Purpose: Rabbit IgG polyclonal antibody for Coxsackievirus and adenovirus receptor(CXADR) detection. Tested with WB in Human,Mouse,Rat.

Sequence: YSKTQYNQVP SEDFER

Cross-Reactivity (Details): Predicted Cross Reactivity: mouse
No cross reactivity with other proteins.
Predicted Cross Reactivity: Species predicted to be fit for the product based on sequence similarities.

Characteristics: Rabbit IgG polyclonal antibody for Coxsackievirus and adenovirus receptor(CXADR) detection. Tested with WB in Human,Mouse,Rat.
Gene Name: coxsackie virus and adenovirus receptor
Protein Name: Coxsackievirus and adenovirus receptor(CAR/hCAR)

Purification: Immunogen affinity purified.

Immunogen: A synthetic peptide corresponding to a sequence at the C-terminus of human Coxsackie Adenovirus Receptor(313-328aa YSKTQYNQVPSEDFER), identical to the related rat and mouse sequences.

Isotype: IgG

Application Details

Application Notes: WB: Concentration: 0.1-0.5 μg/mL, Tested Species: Human, Rat, Predicted Species: Mouse
Notes: Tested Species: Species with positive results. Predicted Species: Species predicted to be fit for the product based on sequence similarities.
Other applications have not been tested. Optimal dilutions should be determined by end users.

Comment:

Antibody can be supported by chemiluminescence kit ABIN921124 in WB.

Restrictions: For Research Use only

Handling

Format: Lyophilized

Reconstitution: Add 0.2 mL of distilled water will yield a concentration of 500 μg/mL.

Concentration: 500 μg/mL

Buffer: Each vial contains 5 mg BSA, 0.9 mg NaCl, 0.2 mg Na2HPO4, 0.05 mg Thimerosal, 0.05 mg Sodium azide.

Preservative: Thimerosal (Merthiolate), Sodium azide

Precaution of Use: This product contains Sodium azide and Thimerosal (Merthiolate): POISONOUS AND HAZARDOUS SUBSTANCES which should be handled by trained staff only.

Handling Advice: Avoid repeated freezing and thawing.

Storage: 4 °C/-20 °C

Storage Comment: At -20°C for one year. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20 °C for a longer time. Avoid repeated freezing and thawing.

Expiry Date: 12 months

Target Details for Coxsackie Adenovirus Receptor

Target: Coxsackie Adenovirus Receptor (CXADR) (Coxsackie Virus and Adenovirus Receptor (CXADR))

Alternative Name: CXADR (CXADR Products)

Synonyms: CAR antibody, CAR4/6 antibody, HCAR antibody, Car1 antibody, car antibody, cb331 antibody, fb76g12 antibody, wu:fb76g12 antibody, 2610206D03Rik antibody, AU016810 antibody, AW553441 antibody, MCAR antibody, MCVADR antibody, hcar antibody, xCAR antibody, CXADR antibody, CXADR, Ig-like cell adhesion molecule antibody, coxsackie virus and adenovirus receptor antibody, CXADR, Ig-like cell adhesion molecule L homeolog antibody, CXADR antibody, Cxadr antibody, cxadr antibody, cxadr.L antibody

Background: CXADR(Coxsackie virus and adenovirus receptor) is a protein that in humans is encoded by the CXADR gene, also known as CAR,CVB3-binding protein, Coxsackievirus B-adenovirus receptor. The CAR cDNA encodes a predicted 365-amino acid polypeptide that contains a single transmembrane domain and is a member of the immunoglobulin superfamily. By Northern blot analysis, they detected highest expression of 1.4-kb and 6-kb CXADR transcripts in pancreas, brain, heart, small intestine, testis, and prostate, lower expression in liver and lung, and no expression in kidney, placenta, peripheral blood leukocytes, thymus, and spleen. In comparison, mouse Cxadr showed highest expression in liver, and lower levels in kidney, heart, lung, and brain. The protein encoded by this gene is a type I membrane receptor for group B coxsackie viruses and subgroup C adenoviruses. Pseudogenes of this gene are found on chromosomes 15, 18, and 21. CAR is strongly expressed in the developing central nervous system. It functions as a homophilic and also as a heterophilic cell adhesion molecule through its interactions with extracellular matrix glycoproteins , such as: fibronectin, agrin, laminin-1 and tenascin-R.

Synonyms: 46 kD coxsackievirus and adenovirus receptor CAR protein antibody|46 kD coxsackievirus and adenovirus receptor protein antibody|CAR antibody|CAR4/6 antibody|Coxsackie virus and adenovirus receptor antibody|Coxsackie virus B receptor antibody|Coxsackievirus and adenovirus receptor antibody|Coxsackievirus B adenovirus receptor antibody|Coxsackievirus B-adenovirus receptor antibody|CVB3 binding protein antibody|CVB3-binding protein antibody|Cxadr antibody|CXAR_HUMAN antibody|hCAR antibody|HCVADR antibody

UniProt: P78310

Pathways: Cell-Cell Junction Organization