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CSF3R antibody (Middle Region)

CSF3R Reactivity: Human WB Host: Rabbit Polyclonal unconjugated
Catalog No. ABIN3044116
  • Target See all CSF3R Antibodies
    CSF3R (Colony Stimulating Factor 3 Receptor (Granulocyte) (CSF3R))
    Binding Specificity
    • 12
    • 7
    • 7
    • 7
    • 6
    • 4
    • 4
    • 3
    • 3
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 254-271, Middle Region
    Reactivity
    • 67
    • 25
    • 22
    • 1
    • 1
    • 1
    • 1
    • 1
    Human
    Host
    • 54
    • 14
    • 2
    • 1
    • 1
    Rabbit
    Clonality
    • 58
    • 14
    Polyclonal
    Conjugate
    • 34
    • 7
    • 6
    • 4
    • 4
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This CSF3R antibody is un-conjugated
    Application
    • 61
    • 30
    • 19
    • 17
    • 9
    • 6
    • 6
    • 4
    • 2
    • 2
    • 2
    • 1
    Western Blotting (WB)
    Purpose
    Rabbit IgG polyclonal antibody for Granulocyte colony-stimulating factor receptor(CSF3R) detection. Tested with WB in Human.
    Sequence
    EPWQPGLHIN QKCELRHK
    Cross-Reactivity (Details)
    No cross reactivity with other proteins.
    Characteristics
    Rabbit IgG polyclonal antibody for Granulocyte colony-stimulating factor receptor(CSF3R) detection. Tested with WB in Human.
    Gene Name: Colony stimulating factor 3 receptor(granulocyte)
    Protein Name: Granulocyte colony-stimulating factor receptor
    Purification
    Immunogen affinity purified.
    Immunogen
    A synthetic peptide corresponding to a sequence in the middle region of human GCSF Receptor(254-271aa EPWQPGLHINQKCELRHK).
    Isotype
    IgG
    Top Product
    Discover our top product CSF3R Primary Antibody
  • Application Notes
    WB: Concentration: 0.1-0.5 μg/mL, Tested Species: Human, The detection limit for CSF3R is approximately 5 ng/lane under reducing conditions.
    Notes: Tested Species: Species with positive results. Predicted Species: Species predicted to be fit for the product based on sequence similarities.
    Other applications have not been tested. Optimal dilutions should be determined by end users.
    Comment

    Antibody can be supported by chemiluminescence kit ABIN921124 in WB.

    Restrictions
    For Research Use only
  • Format
    Lyophilized
    Reconstitution
    Add 0.2 mL of distilled water will yield a concentration of 500 μg/mL.
    Concentration
    500 μg/mL
    Buffer
    Each vial contains 5 mg BSA, 0.9 mg NaCl, 0.2 mg Na2HPO4, 0.05 mg Thimerosal, 0.05 mg Sodium azide.
    Preservative
    Thimerosal (Merthiolate), Sodium azide
    Precaution of Use
    This product contains Sodium azide and Thimerosal (Merthiolate): POISONOUS AND HAZARDOUS SUBSTANCES which should be handled by trained staff only.
    Handling Advice
    Avoid repeated freezing and thawing.
    Storage
    4 °C/-20 °C
    Storage Comment
    At -20°C for one year. After reconstitution, at 4°C for one month.
    It can also be aliquotted and stored frozen at -20 °C for a longer time. Avoid repeated freezing and thawing.
    Expiry Date
    12 months
  • Target
    CSF3R (Colony Stimulating Factor 3 Receptor (Granulocyte) (CSF3R))
    Alternative Name
    CSF3R (CSF3R Products)
    Synonyms
    CD114 antibody, GCSFR antibody, Cd114 antibody, Csfgr antibody, G-CSF-R antibody, G-CSFR antibody, CSF3R antibody, gcsfr antibody, cd114 antibody, colony stimulating factor 3 receptor antibody, colony stimulating factor 3 receptor (granulocyte) antibody, colony stimulating factor 3 receptor L homeolog antibody, granulocyte colony-stimulating factor receptor antibody, CSF3R antibody, Csf3r antibody, csf3r antibody, csf3r.L antibody, LOC100433338 antibody
    Background
    CSF3R(Colony-Stimulating Factor 3 Receptor, Granulocyte) also known as GCSFR or CD114((Cluster of Differentiation 114) is a protein that in humans is encoded by the CSF3R gene. G-CSF-R is a cell-surface receptor for the granulocyte colony-stimulating factor(G-CSF). The G-CSF receptors belongs to a family of cytokine receptors known as the hematopoietin receptor family. The CSF3R gene consists of 17 exons. By in situ hybridization using human CSF3R cDNA as a probe, Inazawa et al.(1991) localized the gene to 1p35-p34.3. The G-CSF-R is a transmembrane receptor that consists of an extracellular ligand-binding portion, a transmembrane domain, and the cytoplasmic portion that is responsible for signal transduction. GCSF-R ligand-binding is associated with dimerization of the receptor and signal transduction through proteins including Jak, Lyn, STAT, and Erk1/2. Dong et al.(2001) reported that the C terminus of CSF3R is required for SHP1 downregulation of CSF3-induced STAT activation. The authors proposed that this mechanism inhibits cell proliferation and survival in response to CSF3.

    Synonyms: CD 114 antibody|CD114 antibody|CD114 antigen antibody|Colony stimulating factor 3 receptor(granulocyte) antibody|Colony stimulating factor 3 receptor antibody|CSF 3R antibody|CSF3R antibody|CSF3R_HUMAN antibody|Csfgr antibody|G CSF R antibody|G-CSF receptor antibody|G-CSF-R antibody|GCSFR antibody|Granulocyte colony stimulating factor receptor antibody|Granulocyte colony stimulating factor receptor precursor antibody|Granulocyte colony-stimulating factor receptor antibody|OTTHUMP00000009703 antibody|OTTHUMP00000009704 antibody|OTTHUMP00000009705 antibody
    UniProt
    Q99062
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