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Lamin B2 antibody (C-Term)

LMNB2 Reactivity: Human, Rat WB, IHC (p), IHC (fro) Host: Rabbit Polyclonal unconjugated
Catalog No. ABIN3044232
  • Target See all Lamin B2 (LMNB2) Antibodies
    Lamin B2 (LMNB2)
    Binding Specificity
    • 15
    • 6
    • 6
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 580-597, C-Term
    Reactivity
    • 53
    • 40
    • 18
    • 10
    • 5
    • 5
    • 4
    • 4
    • 4
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    Human, Rat
    Host
    • 51
    • 17
    Rabbit
    Clonality
    • 48
    • 20
    Polyclonal
    Conjugate
    • 37
    • 3
    • 3
    • 3
    • 3
    • 3
    • 3
    • 3
    • 3
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    This Lamin B2 antibody is un-conjugated
    Application
    • 49
    • 15
    • 14
    • 14
    • 13
    • 13
    • 11
    • 8
    • 7
    • 7
    • 6
    • 2
    • 1
    • 1
    • 1
    Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunohistochemistry (Frozen Sections) (IHC (fro))
    Purpose
    Rabbit IgG polyclonal antibody for Lamin-B2(LMNB2) detection. Tested with WB, IHC-P, IHC-F in Human,Mouse,Rat.
    Sequence
    EEDLFHQQGD PRTTSRGC
    Cross-Reactivity (Details)
    Predicted Cross Reactivity: mouse
    No cross reactivity with other proteins.
    Predicted Cross Reactivity: Species predicted to be fit for the product based on sequence similarities.
    Characteristics
    Rabbit IgG polyclonal antibody for Lamin-B2(LMNB2) detection. Tested with WB, IHC-P, IHC-F in Human,Mouse,Rat.
    Gene Name: lamin B2
    Protein Name: Lamin-B2
    Purification
    Immunogen affinity purified.
    Immunogen
    A synthetic peptide corresponding to a sequence at the C-terminus of human Lamin B2(580-597aa EEDLFHQQGDPRTTSRGC), identical to the related rat and mouse sequences.
    Isotype
    IgG
    Top Product
    Discover our top product LMNB2 Primary Antibody
  • Application Notes
    WB: Concentration: 0.1-0.5 μg/mL, Tested Species: Human, Predicted Species: Mouse, Rat
    IHC-P: Concentration: 0.5-1 μg/mL, Tested Species: Human, Rat, Predicted Species: Mouse, Epitope Retrieval by Heat: Boiling the paraffin sections in 10 mM citrate buffer, pH 6.0, for 20 mins is required for the staining of formalin/paraffin sections.
    IHC-F: Concentration: 0.5-1 μg/mL, Tested Species: Rat, Predicted Species: Human, Mouse
    Notes: Tested Species: Species with positive results. Predicted Species: Species predicted to be fit for the product based on sequence similarities. Other applications have not been tested. Optimal dilutions should be determined by end users.
    Comment

    Antibody can be supported by chemiluminescence kit ABIN921124 in WB, supported by ABIN921231 in IHC(P) and IHC(F).

    Restrictions
    For Research Use only
  • Format
    Lyophilized
    Reconstitution
    Add 0.2 mL of distilled water will yield a concentration of 500 μg/mL.
    Concentration
    500 μg/mL
    Buffer
    Each vial contains 5 mg BSA, 0.9 mg NaCl, 0.2 mg Na2HPO4, 0.05 mg Thimerosal, 0.05 mg Sodium azide.
    Preservative
    Thimerosal (Merthiolate), Sodium azide
    Precaution of Use
    This product contains Sodium azide and Thimerosal (Merthiolate): POISONOUS AND HAZARDOUS SUBSTANCES which should be handled by trained staff only.
    Handling Advice
    Avoid repeated freezing and thawing.
    Storage
    4 °C/-20 °C
    Storage Comment
    At -20°C for one year. After reconstitution, at 4°C for one month.
    It can also be aliquotted and stored frozen at -20 °C for a longer time. Avoid repeated freezing and thawing.
    Expiry Date
    12 months
  • Chen, Jiang, Gu, Lai, Liu, Zhang: "Protection of Nrf2 against arsenite-induced oxidative damage is regulated by the cyclic guanosine monophosphate-protein kinase G signaling pathway." in: Environmental toxicology, Vol. 32, Issue 8, pp. 2004-2020, (2017) (PubMed).

  • Target
    Lamin B2 (LMNB2)
    Alternative Name
    LMNB2 (LMNB2 Products)
    Synonyms
    lmnb2-a antibody, LMNB2 antibody, lmn2 antibody, lamb2 antibody, Lamin-L(II) antibody, LOC100136040 antibody, im:7142331 antibody, lamin antibody, wu:fb94e05 antibody, wu:fb95e12 antibody, wu:fc15d06 antibody, wu:fc49h03 antibody, lamin-b2 antibody, lmnb2 antibody, LAMB2 antibody, LMN2 antibody, RGD1563803 antibody, lamin B2 S homeolog antibody, lamin B2 antibody, lamin B2 L homeolog antibody, lmnb2.S antibody, LMNB2 antibody, lmnb2 antibody, lmnb2.L antibody, Lmnb2 antibody
    Background
    Lamin B2, also called LMNB2, is a protein associated with laminopathies. The LMNB2 gene is mapped to the G-negative subtelomeric band p13.3 of chromosome 19 by in situ hybridization. The LMNB2 gene contains 12 exons. Model organisms have been used in the study of Lamin B2 function. A conditional knockout mouse line, called Lmnb2, is generated as part of the International Knockout Mouse Consortium program-a high-throughput mutagenesis project to generate and distribute animal models of disease to interested scientists. A highly sensitive procedure about mapping the start site of DNA replication in a 13.7-kb region of human chromosome 19 coding for lamin B2 is developed for the identification of the origin of bidirectional DNA synthesis in single-copy replicons of mammalian cells.

    Synonyms: LAMB 2 antibody|LAMB2 antibody|Lamin-B2 antibody|LMN 2 antibody|LMN B2 antibody|LMN2 antibody|LMNB 2 antibody|LMNB2 antibody|LMNB2_HUMAN antibody|MGC2721 antibody|RGD1563803 antibody
    UniProt
    Q03252
    Pathways
    Apoptosis, Caspase Cascade in Apoptosis
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