ABCB6 antibody (C-Term)

Catalog No. ABIN3044283

Product Details anti-ABCB6 Antibody

Target: ABCB6 (ATP-Binding Cassette, Sub-Family B (MDR/TAP), Member 6 (ABCB6))

Binding Specificity: AA 818-842, C-Term

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This ABCB6 antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunocytochemistry (ICC)

Purpose: Rabbit IgG polyclonal antibody for ATP-binding cassette sub-family B member 6, mitochondrial(ABCB6) detection. Tested with WB, IHC-P, ICC in Human.

Sequence: YADMWQLQQG QEETSEDTKP QTMER

Cross-Reactivity (Details): No cross reactivity with other proteins.

Characteristics: Rabbit IgG polyclonal antibody for ATP-binding cassette sub-family B member 6, mitochondrial(ABCB6) detection. Tested with WB, IHC-P, ICC in Human.
Gene Name: ATP-binding cassette, sub-family B(MDR/TAP), member 6
Protein Name: ATP-binding cassette sub-family B member 6, mitochondrial

Purification: Immunogen affinity purified.

Immunogen: A synthetic peptide corresponding to a sequence at the C-terminus of human ABCB6(818-842aa YADMWQLQQGQEETSEDTKPQTMER).

Isotype: IgG

Application Details

Application Notes: WB: Concentration: 0.1-0.5 μg/mL, Tested Species: Human
IHC-P: Concentration: 0.5-1 μg/mL, Tested Species: Human, Epitope Retrieval by Heat: Boiling the paraffin sections in 10 mM citrate buffer, pH 6.0, for 20 mins is required for the staining of formalin/paraffin sections.
ICC: Concentration: 0.5-1 μg/mL, Tested Species: Human
Notes: Tested Species: Species with positive results. Predicted Species: Species predicted to be fit for the product based on sequence similarities. Other applications have not been tested. Optimal dilutions should be determined by end users.

Comment:

Antibody can be supported by chemiluminescence kit ABIN921124 in WB, supported by ABIN921231 in IHC(P) and ICC.

Restrictions: For Research Use only

Handling

Format: Lyophilized

Reconstitution: Add 0.2 mL of distilled water will yield a concentration of 500 μg/mL.

Concentration: 500 μg/mL

Buffer: Each vial contains 5 mg BSA, 0.9 mg NaCl, 0.2 mg Na2HPO4, 0.05 mg Thimerosal, 0.05 mg Sodium azide.

Preservative: Thimerosal (Merthiolate), Sodium azide

Precaution of Use: This product contains Sodium azide and Thimerosal (Merthiolate): POISONOUS AND HAZARDOUS SUBSTANCES which should be handled by trained staff only.

Handling Advice: Avoid repeated freezing and thawing.

Storage: 4 °C/-20 °C

Storage Comment: At -20°C for one year. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20 °C for a longer time. Avoid repeated freezing and thawing.

Expiry Date: 12 months

Target Details for ABCB6

Target: ABCB6 (ATP-Binding Cassette, Sub-Family B (MDR/TAP), Member 6 (ABCB6))

Alternative Name: ABCB6 (ABCB6 Products)

Synonyms: ABCB6 antibody, abcb6 antibody, ABC antibody, ABC14 antibody, LAN antibody, MCOPCB7 antibody, MTABC3 antibody, PRP antibody, umat antibody, 1200005B17Rik antibody, ATP binding cassette subfamily B member 6 (Langereis blood group) antibody, ATP binding cassette subfamily B member 6 antibody, ATP-binding cassette, sub-family B (MDR/TAP), member 6a antibody, ATP-binding cassette, sub-family B (MDR/TAP), member 6 antibody, ABCB6 antibody, abcb6a antibody, abcb6 antibody, Abcb6 antibody

Background: ABCB6, ATP-binding cassette sub-family B member 6, mitochondrialis a protein that in humans is encoded by the ABCB6 gene. The membrane-associated protein encoded by this gene is a member of the superfamily of ATP-binding cassette(ABC) transporters. ABC proteins transport various molecules across extra- and intra-cellular membranes. ABC genes are divided into seven distinct subfamilies(ABC1, MDR/TAP, MRP, ALD, OABP, GCN20, White). This protein is a member of the MDR/TAP subfamily. Members of the MDR/TAP subfamily are involved in multidrug resistance as well as antigen presentation. This half-transporter likely plays a role in mitochondrial function. Localized to 2q26, this gene is considered a candidate gene for lethal neonatal metabolic syndrome, a disorder of mitochondrial function.

Synonyms: ABC antibody|ABC transporter umat antibody|ABC14 antibody|Abcb6 antibody|ABCB6_HUMAN antibody|ATP binding cassette sub family B member 6, mitochondrial precursor antibody|ATP binding cassette, sub family B(MDR/TAP), member 6 antibody|ATP-binding cassette sub-family B member 6 antibody|Mitochondrial ABC transporter 3 antibody|mitochondrial antibody|Mt ABC transporter 3 antibody|Mt-ABC transporter 3 antibody|MTABC3 antibody|P glycoprotein related protein antibody|P-glycoprotein-related protein antibody|PRP antibody|Ubiquitously expressed mammalian ABC half transporter antibody|Ubiquitously-expressed mammalian ABC half transporter antibody|UMAT antibody

Pathways: Transition Metal Ion Homeostasis