FGF23 antibody (AA 48-251)

Catalog No. ABIN3044523

Product Details anti-FGF23 Antibody

Target: FGF23 (Fibroblast Growth Factor 23 (FGF23))

Binding Specificity: AA 48-251

Reactivity: Mouse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This FGF23 antibody is un-conjugated

Application: Western Blotting (WB)

Purpose: Rabbit IgG polyclonal antibody for Fibroblast growth factor 23(FGF23) detection. Tested with WB in Mouse.

Cross-Reactivity (Details): No cross reactivity with other proteins.

Characteristics: Rabbit IgG polyclonal antibody for Fibroblast growth factor 23(FGF23) detection. Tested with WB in Mouse.
Gene Name: fibroblast growth factor 23
Protein Name: Fibroblast growth factor 23

Purification: Immunogen affinity purified.

Immunogen: E. coli-derived mouse FGF23 recombinant protein (Position: R48-V251). Mouse FGF23 shares 71.1% and 94.6% amino acid (aa) sequence identity with human and rat FGF23, respectively.

Isotype: IgG

Application Details

Application Notes: WB: Concentration: 0.1-0.5 μg/mL, Tested Species: Mouse
Notes: Tested Species: Species with positive results.
Other applications have not been tested. Optimal dilutions should be determined by end users.

Comment:

Antibody can be supported by chemiluminescence kit ABIN921124 in WB.

Restrictions: For Research Use only

Handling

Format: Lyophilized

Reconstitution: Add 0.2 mL of distilled water will yield a concentration of 500 μg/mL.

Concentration: 500 μg/mL

Buffer: Each vial contains 5 mg BSA, 0.9 mg NaCl, 0.2 mg Na2HPO4, 0.05 mg Sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freezing and thawing.

Storage: 4 °C/-20 °C

Storage Comment: At -20°C for one year. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20 °C for a longer time. Avoid repeated freezing and thawing.

References for anti-FGF23 antibody (ABIN3044523)

Ji, Ling, Zhang, Chou, Yang, Wang, Yin, Wu, Yu: "MicroRNA-296 mediated corneal neovascularization in an animal model of corneal burns after alkali exposures." in: Experimental and therapeutic medicine, Vol. 15, Issue 1, pp. 139-144, (2018) (PubMed).

Target Details for FGF23

Target: FGF23 (Fibroblast Growth Factor 23 (FGF23))

Alternative Name: FGF23 (FGF23 Products)

Background: Fibroblast growth factor 23 or FGF23 is a protein that in humans is encoded by the FGF23 gene. This gene encodes a member of the fibroblast growth factor family of proteins, which possess broad mitogenic and cell survival activities and are involved in a variety of biological processes. The product of this gene regulates phosphate homeostasis and transport in the kidney. The full-length, functional protein may be deactivated via cleavage into N-terminal and C-terminal chains. Mutation of this cleavage site causes autosomal dominant hypophosphatemic rickets (ADHR). Mutations in this gene are also associated with hyperphosphatemic familial tumoral calcinosis (HFTC).

Synonyms: ADHR antibody|FGF-23 antibody|Fgf23 antibody|FGF23_HUMAN antibody|FGFN antibody|Fibroblast growth factor 23 antibody|Fibroblast growth factor 23 C-terminal peptide antibody|Fibroblast growth factor 23 precursor antibody|HPDR2 antibody|HYPF antibody|Phosphatonin antibody|PHPTC antibody|Tumor derived hypophosphatemia inducing factor antibody|Tumor-derived hypophosphatemia-inducing factor antibody

Gene ID: 64654

Pathways: RTK Signaling, Fc-epsilon Receptor Signaling Pathway, EGFR Signaling Pathway, Neurotrophin Signaling Pathway, Negative Regulation of Hormone Secretion