Prokineticin 1 antibody (AA 20-105)

Catalog No. ABIN3044536

Product Details anti-Prokineticin 1 Antibody

Target: Prokineticin 1 (Prok1)

Binding Specificity: AA 20-105

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This Prokineticin 1 antibody is un-conjugated

Application: Western Blotting (WB), ELISA

Purpose: Rabbit IgG polyclonal antibody for Prokineticin-1(PROK1) detection. Tested with WB, ELISA in Human.

Cross-Reactivity (Details): No cross reactivity with other proteins.

Characteristics: Rabbit IgG polyclonal antibody for Prokineticin-1(PROK1) detection. Tested with WB, ELISA in Human.
Gene Name: prokineticin 1
Protein Name: Prokineticin-1

Purification: Immunogen affinity purified.

Immunogen: E. coli-derived human Prokineticin 1 recombinant protein (Position: A20-F105). Human Prokineticin 1 shares 88.4% and 91.9% amino acid (aa) sequence identity with mouse and rat Prokineticin 1, respectively.

Isotype: IgG

Application Details

Application Notes: WB: Concentration: 0.1-0.5 μg/mL, Tested Species: Human
ELISA: Concentration: 0.1-0.5 μg/mL, Tested Species: Human

Notes: Tested Species: Species with positive results.
Other applications have not been tested. Optimal dilutions should be determined by end users.

Comment:

Antibody can be supported by chemiluminescence kit ABIN921124 in WB.

Restrictions: For Research Use only

Handling

Format: Lyophilized

Reconstitution: Add 0.2 mL of distilled water will yield a concentration of 500 μg/mL.

Concentration: 500 μg/mL

Buffer: Each vial contains 5 mg BSA, 0.9 mg NaCl, 0.2 mg Na2HPO4, 0.05 mg Sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freezing and thawing.

Storage: 4 °C/-20 °C

Storage Comment: At -20°C for one year. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20 °C for a longer time. Avoid repeated freezing and thawing.

References for anti-Prokineticin 1 antibody (ABIN3044536)

Yu, Chen, Jiang: "Administration of pigment epithelium-derived factor delivered by adeno-associated virus inhibits blood-retinal barrier breakdown in diabetic rats." in: Molecular vision, Vol. 16, pp. 2384-94, (2011) (PubMed).

Target Details for Prokineticin 1

Target: Prokineticin 1 (Prok1)

Alternative Name: PROK1 (Prok1 Products)

Synonyms: PK1 antibody, zgc:171925 antibody, EGVEGF antibody, PRK1 antibody, EG-VEGF antibody, prokineticin 1 antibody, PROK1 antibody, prok1 antibody, Prok1 antibody

Background: Prokineticin-1 is also known as EG-VEGF. The International Radiation Hybrid Mapping Consortium mapped the PROK1 gene to chromosome 1. The protein encoded by this gene induces proliferation, migration, and fenestration (the formation of membrane discontinuities) in capillary endothelial cells derived from endocrine glands. It has little or no effect on a variety of other endothelial and non-endothelial cell types. Its expression is restricted to the steroidogenic glands (ovary, testis, adrenal, and placenta), is induced by hypoxia, and often complementary to the expression of vascular endothelial growth factor (VEGF), suggesting that these molecules function in a coordinated manner.

Synonyms: Black mamba toxin related protein antibody|EG VEGF antibody|EG-VEGF antibody|EGVEGF antibody|Endocrine-gland-derived vascular endothelial growth factor antibody|Mambakine antibody|PK1 antibody|PRK1 antibody|PROK1 antibody|PROK1_HUMAN antibody|Prokineticin-1 antibody

Gene ID: 84432

UniProt: P58294