TRPM4 antibody (AA 1079-1214)

Catalog No. ABIN3044557

Product Details anti-TRPM4 Antibody

Target: TRPM4 (Transient Receptor Potential Cation Channel, Subfamily M, Member 4 (TRPM4))

Binding Specificity: AA 1079-1214

Reactivity: Human, Mouse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This TRPM4 antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Purpose: Rabbit IgG polyclonal antibody for Transient receptor potential cation channel subfamily M member 4(TRPM4) detection. Tested with WB, IHC-P in Human,Mouse.

Cross-Reactivity (Details): No cross reactivity with other proteins.

Characteristics: Rabbit IgG polyclonal antibody for Transient receptor potential cation channel subfamily M member 4(TRPM4) detection. Tested with WB, IHC-P in Human,Mouse.
Gene Name: transient receptor potential cation channel subfamily M member 4
Protein Name: Transient receptor potential cation channel subfamily M member 4

Purification: Immunogen affinity purified.

Immunogen: E.coli-derived human TRPM4 recombinant protein (Position: F1079-D1214). Human TRPM4 shares 76.8% and 77.8% amino acid (aa) sequence identity with mouse and rat TRPM4, respectively.

Isotype: IgG

Application Details

Application Notes: WB: Concentration: 0.1-0.5 μg/mL, Tested Species: Human, Mouse
IHC-P: Concentration: 0.5-1 μg/mL, Tested Species: Human, Epitope Retrieval by Heat: Boiling the paraffin sections in 10 mM citrate buffer, pH 6.0, for 20 mins is required for the staining of formalin/paraffin sections.
Notes: Tested Species: Species with positive results. Other applications have not been tested. Optimal dilutions should be determined by end users.

Comment:

Antibody can be supported by chemiluminescence kit ABIN921124 in WB, supported by ABIN921231 in IHC(P).

Restrictions: For Research Use only

Handling

Format: Lyophilized

Reconstitution: Add 0.2 mL of distilled water will yield a concentration of 500 μg/mL.

Concentration: 500 μg/mL

Buffer: Each vial contains 5 mg BSA, 0.9 mg NaCl, 0.2 mg Na2HPO4, 0.05 mg Sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freezing and thawing.

Storage: 4 °C/-20 °C

Storage Comment: At -20°C for one year. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20 °C for a longer time. Avoid repeated freezing and thawing.

Target Details for TRPM4

Target: TRPM4 (Transient Receptor Potential Cation Channel, Subfamily M, Member 4 (TRPM4))

Alternative Name: TRPM4 (TRPM4 Products)

Synonyms: PFHB1B antibody, TRPM4B antibody, LTrpC-4 antibody, Mls2s antibody, 1110030C19Rik antibody, AW047689 antibody, LTRPC4 antibody, TRPM4 antibody, transient receptor potential cation channel subfamily M member 4 antibody, transient receptor potential cation channel, subfamily M, member 4 antibody, TRPM4 antibody, Trpm4 antibody

Background: Transient receptor potential cation channel subfamily M member 4 (hTRPM4), also known as melastatin-4, is a protein that in humans is encoded by the TRPM4 gene. It is mapped to 19q13.33. The protein encoded by this gene is a calcium-activated nonselective ion channel that mediates transport of monovalent cations across membranes, thereby depolarizing the membrane. The activity of the encoded protein increases with increasing intracellular calcium concentration, but this channel does not transport calcium. Two transcript variants encoding different isoforms have been found for this gene.

Synonyms: 1110030C19Rik antibody|AW047689 antibody|Calcium-activated non-selective cation channel 1 antibody|FLJ20041 antibody|hTRPM4 antibody| Long transient receptor potential channel 4 antibody|LTrpC-4 antibody|LTrpC4 antibody|Melastatin 4 antibody|Melastatin like 2 protein antibody|Melastatin-4 antibody|Melastatin-like 2 antibody|Mls2s antibody|PFHB1B antibody|Transient receptor potential cation channel subfamily M member 4 antibody|Transient receptor potential cation channel, subfamily M, member 4 antibody|Trpm4 antibody|TRPM4_HUMAN antibody|TRPM4B antibody

Gene ID: 54795

Pathways: Regulation of Leukocyte Mediated Immunity, Production of Molecular Mediator of Immune Response