14-3-3 protein (C-Term) antibody

Antigen: 14-3-3 protein (C-Term)

Clonality: Polyclonal

Host: Rabbit

Reactivity: Rat (Rattus)

Application: Western Blotting (WB)

Catalog no.: ABIN304779

Additional Information

Immunogen: Peptide corresponding to amino acid residues from the C-terminal region of the 14-3-3 protein, conjugated to keyhole limpet hemocyanin (KLH).

Description: Gene: 14-3-3

Specificity: Recognizes rat 14-3-3 protein, a highly conserved, ubiquitously expressed protein family.14-3-3 proteins form homo- and heterodimers that can interact with a variety of cellular proteins that are typically phosphorylated on serine or threonine residues.14-3-3 proteins regulate cellular processes such as trafficking, cell-cycle regulatory pathways and signal transduction. Brain tissue contains the highest concentration of 14-3-3 proteins and the proteins have been found in the cerebral spinal fluid of patients with certain neurodegenerative disease such as Creutzfeldt-Jakob disease and scrapie.14-3-3 proteins might also contribute to Alzheimer's and Parkinson's diseases, Miller-Dieker syndrome and spinocerebellar ataxia type 1.14-3-3 has also been implicated in cancer Predicted Reactivities: Cow (Bovine),Chicken,Dog (Canine),Xenopus laevis,Human,Mouse (Murine).

Application Details

Application Notes: WB (1:1000)

Purification: Affinity Chromatography

Buffer: 10 mM HEPES, pH 7.5, 150 mM sodium chloride, 0.09% sodium azide, 50% glycerol, 0.01% BSA.

Storage: Long term: -20°C, Short term: -20°C

Restrictions: For Research Use only