TNNC1 antibody
| Antigen |
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| Clonality |
Monoclonal (7B9) |
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Host
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Reactivity
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Application
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| Catalog no. |
ABIN305098 |
| Quantity |
200 µg (Variants) |
| Price |
426.67 $ Plus shipping costs $35.00
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| Shipping to |
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| Availability |
Ships within 10 to 15 Business Days |
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Swiss-Prot
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P63316
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Immunogen
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Human slow skeletal troponin C.
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Isotype
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IgG1 (Matching secondary antibodies)
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Clone
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7B9
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Description
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Gene: TNNC1, Standard Gene Symbol: TNNC1, Synonyms: TNNC1, CMD1Z, CMH13, TN-C, TNC, TNNC, Troponin c, slow skeletal and cardiac muscles
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Specificity
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Recognizes human Troponin C, an 18kD subunit of the Troponin complex found on actin filaments in muscle tissue. Troponin C (TnC) is responsible for binding calcium ions. In the absence of calcium, TnC has an inhibitory action on the actin filaments. When calcium binds to TnC, a conformational change takes place in Troponin I, which in turn causes a change in another associated protein, tropomyosin. Troponin and tropomyosin is repositioned away from the actin filaments, leaving the myosin binding sites available for cross-bridges to form and muscle contraction to occur. Recognizes free cardiac Troponin C and TnC in binary complex with cardiac Troponin I. The antibody does not recognize free cardiac Troponin I or cardiac Troponin T. May be used to detect human Troponin C in ELISA assays.
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Application Notes
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ELISA, WB
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Purification
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Affinity Chromatography
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Buffer
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PBS, pH 7.4, 0.09% sodium azide.
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Storage
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Long term: -20°C, Short term: -20°C
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Restrictions
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For Research Use only
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Alternatives for antigen "TNNC1", type "Antibodies"
Alternatives 
