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ABCB11 antibody (AA 705-718)

ABCB11 Reactivity: Human WB, IHC, ICC, IHC (p) Host: Mouse Monoclonal unconjugated
Catalog No. ABIN305775
  • Target See all ABCB11 Antibodies
    ABCB11 (ATP-Binding Cassette, Sub-Family B (MDR/TAP), Member 11 (ABCB11))
    Binding Specificity
    • 7
    • 7
    • 4
    • 4
    • 3
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 705-718
    Reactivity
    • 28
    • 16
    • 6
    Human
    Host
    • 30
    • 3
    Mouse
    Clonality
    • 30
    • 3
    Monoclonal
    Conjugate
    • 19
    • 3
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This ABCB11 antibody is un-conjugated
    Application
    • 19
    • 12
    • 11
    • 7
    • 5
    • 4
    • 2
    • 1
    • 1
    Western Blotting (WB), Immunohistochemistry (IHC), Immunocytochemistry (ICC), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
    Brand
    IHC-plus™
    Specificity
    Recognizes human BSEP. Does not cross-react with human P-glycoprotein.
    Predicted Reactivity
    Percent identity by BLAST analysis: Human, Gorilla, Gibbon, Monkey, Panda (100%) Marmoset, Dog (93%).
    Purification
    Protein G purified
    Immunogen
    Synthetic peptide corresponding to aa 705-718 (Y705LVHEPPLAVVDHK718) of human BSEP (bile salt export pump). Percent identity by BLAST analysis: Human, Gorilla, Gibbon, Monkey, Panda (100%), Marmoset, Dog (93%).

    Type of Immunogen: Synthetic peptide
    Isotype
    IgG1
    Top Product
    Discover our top product ABCB11 Primary Antibody
  • Application Notes
    Approved: ICC, IHC, IHC-P (5 μg/mL), WB

    Usage: Immunohistochemistry: This antibody was validated for use in immunohistochemistry on a panel of 21 formalin-fixed, paraffin-embedded (FFPE) human tissues after heat induced antigen retrieval in  pH 6.0 citrate buffer. After incubation with the primary antibody, slides were incubated with biotinylated secondary antibody, followed by alkaline phosphatase-streptavidin and chromogen. The stained slides were evaluated by a pathologist to confirm staining specificity. The optimal working concentration for this antibody was determined to be 5 μg/mL.Western Blot: 1:50-1:200Immunocytochemistry: Cytospin preparationsOptimal dilutions to be determined by the researcher.
    Comment

    Target Species of Antibody: Human

    Restrictions
    For Research Use only
  • Format
    Liquid
    Concentration
    Lot specific
    Buffer
    PBS  pH 7.2, 0.7 % BSA, 100nM sodium azide
    Preservative
    Sodium azide
    Precaution of Use
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Handling Advice
    Avoid repeat freeze-thaw cycles.
    Storage
    4 °C,-20 °C
    Storage Comment
    Short term: 4°C. Long term: Store at -20°C. Avoid freeze-thaw cycles.
  • Target
    ABCB11 (ATP-Binding Cassette, Sub-Family B (MDR/TAP), Member 11 (ABCB11))
    Alternative Name
    ABCB11 / BSEP (ABCB11 Products)
    Synonyms
    ABCB11 antibody, Bsep antibody, ABC16 antibody, BRIC2 antibody, BSEP antibody, PFIC-2 antibody, PFIC2 antibody, PGY4 antibody, SPGP antibody, Lith1 antibody, BSEP/SPGP antibody, Spgp antibody, ATP binding cassette subfamily B member 11 antibody, bile salt export pump antibody, ATP-binding cassette, sub-family B (MDR/TAP), member 11 antibody, ABCB11 antibody, LOC100489744 antibody, LOC100565276 antibody, EDI_111220 antibody, EDI_272930 antibody, abcb11 antibody, Abcb11 antibody
    Background
    Name/Gene ID: ABCB11
    Subfamily: ATP-binding cassette - ABCB/MDR
    Family: Transporter

    Synonyms: ABCB11, ABC16, Bile salt export pump, BSEP, PGY4, Sister p-glycoprotein, BRIC2, PFIC-2, PFIC2, SPGP
    Gene ID
    8647
    UniProt
    O95342
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