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Apoptotic Chromatin Condensation Inducer 1 (ACIN1) (internal) antibody
| Antigen | Apoptotic Chromatin Condensation Inducer 1 (ACIN1) |
| Synonyms |
ACN, ACINUS, fSAP152, KIAA0670, DKFZp667N107, Acn, Acinus, C79325, acinusL, acinusS, mKIAA0670, 2610036I19Rik, 2610510L13Rik, acinus, acinusb, fi14c05, wu:fe06a10, wu:fi14c05, acinusa, acinusl, wu:fb0 ...
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| Epitope |
 Alternatives internal |
| Clonality | Polyclonal |
| Host |
Alternatives Rabbit |
| Reactivity |
Alternatives Human |
| Application |
Alternatives Western Blotting (WB)
|
| Catalog no. | ABIN306734 |
| Quantity | 100 ug (0.5 mg/ml) |
| Price | 245.00 $ Plus shipping costs $35.00 |
| Shipping to |
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| Availability | Ships within 5 to 10 Business Days |
Additional Information
| Alternative name | Acinus (IN) |
| Swiss-Prot | Q9UKV3 |
| Isotype | IgG (Matching secondary antibodies) |
| Description | Chromatin condensation and nuclear fragmentation (CCNF) is the hallmark of apoptosis. CCNF is triggered by the activation of members of the caspase family, caspase activated DNase (CAD/DFF40), and several novel proteins including AIF and CIDE (1). A new inducer of chromatin condensation was recently identified and designated Acinus (for apoptotic chromatin condensation inducer in the nucleus). Acinus is cleaved by caspase-3 and an additional unknown protease generating a small active peptide p17, which causes chromatin condensation in vitro when it is added to purified nuclei. Acinus also induces apoptotic chromatin condensation in cells. Acinus is ubiquitously expressed. Three different spliced forms of Acinus have been identified in human and mouse and designated AcinusL, AcinusS and AcinusS' (2). Synonyms: Apoptotic chromatin condensation inducer in the nucleus, ACINUS, KIAA0670. |
| Synonyms | ACN, ACINUS, fSAP152, KIAA0670, DKFZp667N107, Acn, Acinus, C79325, acinusL, acinusS, mKIAA0670, 2610036I19Rik, 2610510L13Rik, acinus, acinusb, fi14c05, wu:fe06a10, wu:fi14c05, acinusa, acinusl, wu:fb04g06, wu:fb40f03, wu:fb68h03, wu:fb80f07, wu:fc12e10, ik:tdsubc_2g5, si:zc14a17.12, xx:tdsubc_2g5, acn, MGC69430, MGC132201 |
Application Details
| Application Notes | Detects Acinus by Western blot at 0.5 to 1.0 ug/ml. Detects a 220 kDa band in K562 cell lysate. Positive Control: K562 cell lysate. |
| Concentration | 0.5 mg/ml |
| Storage | Product should be stored at -20C. Aliquot to avoid freeze/thaw cycles |
| Research Area | Cell Cycle, Apoptosis/Necrosis |
| Restrictions | For Research Use only |
Alternatives
Alternatives for antigen "Apoptotic Chromatin Condensation Inducer 1 (ACIN1)", type "Antibodies"
| Hosts | Rabbit (59) |
| Reactivities | Human (56), Mouse (Murine) (19), Rat (Rattus) (16), Cow (Bovine) (15), Dog (Canine) (15), Horse (Equine) (15) |
| Applications | Western Blotting (WB) (47), Immunofluorescence (IF) (19), Flow Cytometry (FACS) (13), Enzyme Immunoassay (EIA) (7), ELISA (3), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)) (3), Immunohistochemistry (Formalin-fixed Sections) (IHC (f)) (2), Immunoprecipitation (IP) (2), Immunoelectron Microscopy (EM) (1) |
| Conjugates | Alexa Flour 488 (1), Biotin (1), Cy3 (1), Cy5 (1), Cy5.5 (1), Cy7 (1), FITC (1), Gold (1), HRP (1), PE (1), PE,Cy3 (1), PE,Cy5 (1), PE,Cy7 (1), RBITC (1) |
| Epitopes | C-Term (5), N-Term (1), cytoplasm. domain (1), p17-C-Term (1), p17-N-Term (1) |
