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Antibodies
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anti-BCL2/adenovirus E1B 19kDa Interacting Protein 3-Like (BNIP3L) (internal) anti...
BCL2/adenovirus E1B 19kDa Interacting Protein 3-Like (BNIP3L) (internal) antibody
| Antigen |
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| Synonyms |
NIX, BNIP3a, Nix |
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Epitope
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| Clonality |
Polyclonal |
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Host
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Reactivity
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Application
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Immunofluorescence (IF) (19), Flow Cytometry (FACS) (18), Western Blotting (WB) (16), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)) (11), Enzyme Immunoassay (EIA) (5), ELISA (3), Immunohistochemistry (Formalin-fixed Sections) (IHC (f)) (2), Immunoprecipitation (IP) (2), ELISA (Detection) (1), Immunoelectron Microscopy (IEM) (1), Immunohistochemistry (IHC) (1)
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| Catalog no. |
ABIN306750 |
| Quantity |
100 ug (0.5 mg/ml) |
| Price |
245.00 $ Plus shipping costs $35.00
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| Shipping to |
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| Availability |
Ships within 5 to 7 Business Days |
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Alternative name
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Bnip3L (IN) (nix) (bcl 2 family)
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Swiss-Prot
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O60238
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Isotype
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IgG (Matching secondary antibodies)
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Description
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Members in the Bcl-2 family are critical regulators of apoptosis by either inhibiting or promoting cell death. Bcl-2 homology 3 (BH3) domain is a potent death domain. BH3 domain containing pro-apoptotic proteins, including Bad, Bax, Bid, Bik, Hrk, Nip3, and Bim, form a growing subclass of the Bcl-2 family. A novel BH3 domain containing protein was recently identified and designated Bnip3L, Bnip3 , and Nix (for Nip3-like protein X) (1-3). Bnip3L/Bnip3 /Nix is a homolog of the E1B 19K/Bcl-2 binding and pro-apoptotic protein Bnip3. Overexpression of Bnip3L induces apoptosis (2,3). Bnip3L interacts with and overcomes suppresses by Bcl-2 and Bcl-xL. Bnip3L is localized in mitochondria. The messenger RNA of Bnip3L is ubiquitously expressed in human tissues (1,2). Bnip3L and Bnip3 form a new subfamily of the pro-apoptotic mitochondrial proteins. Synonyms: BNIP3A, BNIP3H, NIX.
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Application Notes
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Detects Bnip3L by Western blot at 0.5 to 1 ug/ml. Detects a 40 kDa band in K562 cell lysate which represents the monomer of Bnip3L. Positive Control: K562 cell lysate.
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Concentration
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0.5 mg/ml
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Storage
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Product should be stored at -20C. Aliquot to avoid freeze/thaw cycles
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Restrictions
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For Research Use only
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Alternatives for antigen "BCL2/adenovirus E1B 19kDa Interacting Protein 3-Like (BNIP3L)", type "Antibodies"
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Hosts
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Rabbit (35), Mouse (3)
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Reactivities
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Human (35), Mouse (Murine) (20), Rat (Rattus) (18), Cow (Bovine) (16), Pig (Porcine) (16), Rabbit (16), Horse (Equine) (15), Chicken (1), Zebrafish (Brachydanio rerio) (1)
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Applications
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Immunofluorescence (IF) (19), Flow Cytometry (FACS) (18), Western Blotting (WB) (16), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)) (11), Enzyme Immunoassay (EIA) (5), ELISA (3), Immunohistochemistry (Formalin-fixed Sections) (IHC (f)) (2), Immunoprecipitation (IP) (2), ELISA (Detection) (1), Immunoelectron Microscopy (IEM) (1), Immunohistochemistry (IHC) (1)
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Conjugates
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Alexa Flour 488 (1), Alexa Fluor 350 (1), Alexa Fluor 488 (1), Alexa Fluor 555 (1), Alexa Fluor 647 (1), Biotin (1), Cy3 (1), Cy5 (1), Cy5.5 (1), Cy7 (1), FITC (1), Gold (1), HRP (1), PE (1), PE,Cy3 (1), PE,Cy5 (1), PE,Cy5.5 (1), PE,Cy7 (1), RBITC (1)
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Epitopes
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AA 77-92 (1), internal (1)
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Alternatives 
