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Amyloid beta (A4) Precursor Protein (APP) (C-Term) antibody

Antigen

Amyloid beta (A4) Precursor Protein (APP)
Synonyms APP, APP-like, APPL, Abeta, BcDNA:GH04413, EG:65F1.5, DmelCG7727, CG7727, AAA, AD1, PN2, ABPP, APPI, CVAP, ABETA, CTFgamma, aaa, ad1, pn2, abpp, appi, cvap, abeta, MGC88882, ctfgamma
Epitope
Alternatives

C-Term
Clonality Polyclonal
Host
Alternatives

Rabbit
Reactivity
Alternatives

Human, Mouse (Murine), Rat (Rattus)
Application
Alternatives Western Blotting (WB)
Catalog no. ABIN306764
Quantity 100 ug  (0.5 mg/ml)
Price 245.00 $   Plus shipping costs $35.00
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Availability Ships within 5 to 7 Business Days

Additional Information
Application Details Alternatives Secondary Antibodies back to top

Alternative name Amyloid Precursor Protein (APP) (CT)
Swiss-Prot P05067
Isotype IgG  (Matching secondary antibodies)
Description Accumulation of the amyloid- peptide (A ) in the cerebral cortex is a critical event in the pathogenesis of Alzheimer's disease. The amyloid protein precursor (APP) is cleaved by secretase, producing a soluble derivative of the protein and a membrane anchored 99-amino acid carboxy-terminal fragment (C99). The C99 fragment serves as substrate for secretase to generate the 4 kDa amyloid- peptide (A ), which is deposited in the brains of all suffers of Alzheimer's disease. Synonyms: Alzheimer disease amyloid protein, ABPP. APPI, PreA4, Cerebral vascular amyloid peptide.

Application Details
Alternatives Secondary Antibodies back to top

Application Notes Detects APP and C99 fragment by Western blot at 0.5 to 1 ug/ml. Detects an approximately 120 kDa band in human, mouse and rat brain tissue lysates. Positive Control: Murine brain lysate.
Concentration 0.5 mg/ml
Storage Product should be stored at -20C. Aliquot to avoid freeze/thaw cycles
Restrictions For Research Use only

Alternatives
Application Details Secondary Antibodies back to top

Alternatives for antigen "Amyloid beta (A4) Precursor Protein (APP)", type "Antibodies"
Hosts Rabbit (133), Mouse (62), Goat (22)
Reactivities Human (168), Mouse (Murine) (55), Rat (Rattus) (36), Dog (Canine) (5), Monkey (5), Chicken (4), Cow (Bovine) (4), Pig (Porcine) (3), Guinea Pig (2), Rabbit (2), Primate (1)
Applications Western Blotting (WB) (188), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)) (55), ELISA (47), Enzyme Immunoassay (EIA) (47), Immunofluorescence (IF) (38), Immunohistochemistry (IHC) (36), Flow Cytometry (FACS) (18), Immunoprecipitation (IP) (18), Immunohistochemistry (Frozen Sections) (IHC (fro)) (13), Dot Blot (Dot) (6), Immunocytochemistry (ICC) (3), Radioimmunoassay (RIA) (2)
Conjugates FITC (1)
Epitopes variant 1 (10), C-Term (8), N-Term (5), p668 (4), AA 653-662 (3), pThr668 (3), AA 292-312 (2), AA 44-63 (2), AA 671-685 (2), AA 747-761 (2), Ab-730 (2), pSer198 (2), pSer730 (2), pTyr756 (2), AA 1-14 (1), AA 350-450 (1), C-Term D672 (1), Carboxyl Terminal amino acids 737-751 (1), KPI Domain (1), Y756 (1), all isoforms (1), pS198 (1), pS730 (1), pThr743/668 (1)