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Antibodies
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anti-X-Ray Repair Complementing Defective Repair in Chinese Hamster Cells 6 (XRCC6...
X-Ray Repair Complementing Defective Repair in Chinese Hamster Cells 6 (XRCC6) antibody
| Antigen |
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| Synonyms |
ML8, KU70, TLAA, CTC75, CTCBF, G22P1, XRCC6, MGC82304, DKFZp459H0114 |
| Clonality |
Monoclonal (N3H10) |
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Host
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Reactivity
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Application
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Western Blotting (WB) (39), Immunofluorescence (IF) (17), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)) (16), Immunoprecipitation (IP) (11), Enzyme Immunoassay (EIA) (8), ELISA (6), Immunohistochemistry (IHC) (5), Dot Blot (Dot) (1), Gel Shift (GS) (1), Immunocytochemistry (ICC) (1), Immunohistochemistry (Frozen Sections) (IHC (fro)) (1)
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| Catalog no. |
ABIN306843 |
| Quantity |
100 ug (1 mg/ml) |
| Price |
350.00 $ Plus shipping costs $35.00
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| Shipping to |
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| Availability |
Ships within 5 to 7 Business Days |
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Alternative name
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Ku (p70)
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Isotype
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IgG2b (Matching secondary antibodies)
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Clone
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N3H10
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Description
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Recognizes a protein of 70kDa, identified as p70 subunit of Ku. The epitope of this antibody maps between amino acids 506-541 of p70. The Ku autoantigen is a heterodimer of 70kDa (p70) and ~80kDa (p80) proteins. The p70/p80 dimer is important for function of a 460kDa DNA-dependent protein kinase (DNA-PK) that phosphorylates certain transcription factors, including Sp1, Oct-1, p53, and SV40 large T antigen in vitro.
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Application Notes
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This antibody can be used for ELISA, immunofluorescence, Western blotting (0.25-0.5 ug/ml) and immunohistochemistry on frozen and formalin/paraffin sections (1-2 ug/ml). Positive Control: BT474, HeLa, human K562, HL-60, HEp-2, HeLa, Cos-1 cells.
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Concentration
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1 mg/ml
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Storage
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Product should be stored at -20C. Aliquot to avoid freeze/thaw cycles
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Restrictions
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For Research Use only
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Alternatives for antigen "X-Ray Repair Complementing Defective Repair in Chinese Hamster Cells 6 (XRCC6)", type "Antibodies"
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Hosts
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Mouse (22), Rabbit (14), Goat (6)
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Reactivities
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Human (40), Monkey (6), Mouse (Murine) (4), Xenopus laevis (2), Rat (Rattus) (1)
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Applications
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Western Blotting (WB) (39), Immunofluorescence (IF) (17), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)) (16), Immunoprecipitation (IP) (11), Enzyme Immunoassay (EIA) (8), ELISA (6), Immunohistochemistry (IHC) (5), Dot Blot (Dot) (1), Gel Shift (GS) (1), Immunocytochemistry (ICC) (1), Immunohistochemistry (Frozen Sections) (IHC (fro)) (1)
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Epitopes
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N-Term (4)
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