Actin, alpha 2, Smooth Muscle, Aorta (ACTA2) antibody

Antigen: Actin, alpha 2, Smooth Muscle, Aorta (ACTA2)

Synonyms: AAT6, ACTSA, Actvs, a-SMA, SMalphaA, 0610041G09Rik, wu:fb63d03, MGC78870, ACTA2, actc1, actsa, MGC89192, MGC127800, ACT-4, DKFZp469E0314, Acta2, asma, acta, cftd, mpfd, nem1, nem2, nem3, acta2, cftd1, cftdm, MGC52636, MGC79039

Clonality: Monoclonal (A-SM1)

Host: Mouse

Reactivity: Human, Rat (Rattus), Chicken

Application: Western Blotting (WB)

Catalog no.: ABIN306958

Additional Information

Alternative name: Actin (alpha Smooth Muscle)

Isotype: IgG2a  (Matching secondary antibodies)

Clone: A-SM1

Description: Among the six actin isoforms described in mammals, two are found in virtually all cells ( and cytoplasmic), two are detected in smooth muscle cells ( and -smooth muscle) and two are present in striated muscles, one predominantly in skeletal ( -skeletal) and one in cardiac ( -cardiac) muscle cells. These actin isoforms differ slightly in their N-terminus and the sequences of each of them are perfectly conserved in higher vertebrates. Alpha-smooth muscle actin is abundant in vascular and visceral smooth muscle cells. In addition, it has also been shown to appear in stress fibers of fibroblastic cells during pathological situations involving contractile phenomena such as wound healing and fibrocontractive diseases.

Synonyms: AAT6, ACTSA, Actvs, a-SMA, SMalphaA, 0610041G09Rik, wu:fb63d03, MGC78870, ACTA2, actc1, actsa, MGC89192, MGC127800, ACT-4, DKFZp469E0314, Acta2, asma, acta, cftd, mpfd, nem1, nem2, nem3, acta2, cftd1, cftdm, MGC52636, MGC79039

Application Details

Application Notes: Antibody can be used for Western blotting (1:10,000-1:50,000), immunohistochemistry on paraffin-embedded or frozen tissues (1:1000-1:10,000), immunocytochemistry, immuno electron microscopy and ELISA.

Concentration: 1 mg/ml

Storage: Product should be stored at -20C. Aliquot to avoid freeze/thaw cycles

Research Area: Extracellular Matrix

Restrictions: For Research Use only