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Amyloid beta (Abeta) (AA 1-16) antibody

Antigen

Amyloid beta (Abeta)
Synonyms AAA, AD1, PN2, ABPP, APPI, CVAP, ABETA, CTFgamma, aaa, ad1, pn2, abpp, appi, cvap, abeta, MGC88882, ctfgamma, APP
Epitope
Alternatives

AA 1-16
Clonality Monoclonal (6-00E-10)
Host
Alternatives

Mouse
Reactivity
Alternatives

Human
Application
Alternatives Immunohistochemistry (IHC)
Catalog no. ABIN307037
Quantity 100 ug  (1 mg/ml)
Price 285.00 $   Plus shipping costs $35.00
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Availability Ships within 5 to 7 Business Days

Additional Information
Application Details Alternatives Secondary Antibodies back to top

Alternative name beta-Amyloid (Abeta) [1-16]
Swiss-Prot P05067
Isotype IgG1  (Matching secondary antibodies)
Clone 6-00E-10
Description Beta-amyloid peptides are lipophilic metal chelators with metal-reducing activity. They bind transient metals such as copper, zinc and iron. and in vitro, can reduce Cu(2+) and Fe(3+) to Cu(+) and Fe(2+), respectively. Beta-amyloid peptides bind to lipoproteins and apolipoproteins E and J in the CSF and to HDL particles in plasma, inhibiting metal-catalyzed oxidation of lipoproteins. Promotes both tau aggregation and TPK II-mediated phosphorylation. Interaction with overexpressed HADH2 leads to oxidative stress and neurotoxicity.1 The gamma-CTF peptides as well as the caspase-cleaved peptides, including C31, are potent enhancers of neuronal apoptosisSynonyms: APP.

Application Details
Alternatives Secondary Antibodies back to top

Application Notes The antibody has been used in the immunohistochemical detection of A in fixed sections of Alzheimer
Concentration 1 mg/ml
Storage Product should be stored at -20C. Aliquot to avoid freeze/thaw cycles
Restrictions For Research Use only

Alternatives
Application Details Secondary Antibodies back to top

Alternatives for antigen "Amyloid beta (Abeta)", type "Antibodies"
Hosts Rabbit (103), Mouse (58)
Reactivities Human (130), Mouse (Murine) (70), Rat (Rattus) (64), Chicken (45), Cow (Bovine) (45), Dog (Canine) (45), Pig (Porcine) (45), Rabbit (45), Guinea Pig (30), Horse (Equine) (30)
Applications Western Blotting (WB) (77), Immunofluorescence (IF) (68), Flow Cytometry (FACS) (52), ELISA (44), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)) (38), Immunohistochemistry (IHC) (22), Enzyme Immunoassay (EIA) (20), Immunoprecipitation (IP) (18), Immunohistochemistry (Frozen Sections) (IHC (fro)) (10), Immunocytochemistry (ICC) (9), Immunohistochemistry (Formalin-fixed Sections) (IHC (f)) (8), Immunoelectron Microscopy (IEM) (4), Dot Blot (Dot) (1), Radioimmunoassay (RIA) (1)
Conjugates Biotin (9), FITC (6), Alexa Flour 488 (4), Cy3 (4), Cy5 (4), Cy5.5 (4), Cy7 (4), Gold (4), HRP (4), PE (4), PE,Cy3 (4), PE,Cy5 (4), PE,Cy7 (4), RBITC (4)
Epitopes AA 1-28 (30), AA 25-35 (17), AA 31-35 (15), AA 1-40 (9), N-Term (9), AA 1-42 (6), C-Term (5), AA 1-14 (4), AA 1-8 (4), AA 1-17 (3), AA 3-16 (2), AA 32-40 (2), AA 17-42 (1), AA 7-18 (1), AA 8-17 (1), C-Term AA 1-43 (1), C-Term aa1-40 (1), C-Term aa1-42 (1), Oligomer-Specific (1)