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V-Akt Murine Thymoma Viral Oncogene Homolog 1 (AKT1) antibody
| Antigen | V-Akt Murine Thymoma Viral Oncogene Homolog 1 (AKT1) |
| Synonyms |
AKT, PKB, RAC, PRKBA, MGC99656, PKB-ALPHA, RAC-ALPHA, Akt, pkb, xAct, akt-1, v-akt, v-akt1, AKT1, AKT/PKB, D-Akt, DAKT1, DAKT1/PKB, DPKB, DRAC-PK, DRAC-PK66; DRAC-PK85, Dakt, PKB/AKT, PKB/dAKT, RacPK, ...
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| Clonality | Monoclonal (9Q7) |
| Host |
 Alternatives Mouse |
| Reactivity |
Alternatives Human, Mouse (Murine), Rat (Rattus) |
| Application |
Alternatives Western Blotting (WB)
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| Catalog no. | ABIN307039 |
| Quantity | 100 ug |
| Price | 250.00 $ Plus shipping costs $35.00 |
| Shipping to |
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| Availability | Ships within 5 to 10 Business Days |
Additional Information
| Alternative name | Akt |
| Swiss-Prot | P31749 |
| Isotype | IgG3 (Matching secondary antibodies) |
| Clone | 9Q7 |
| Description | AKT is a serine/threonine kinase that plays an important role in multiple biological responses including metabolism, cell survival and growth by phosphorylating many proteins including GSK-3 , caspase-9, BAD, and the Forkhead Transcription Factor. AKT is activated by PI3K, which in turn can interact with FAK and other cytoskeletal-associated proteins, thereby linking activation to the cytoskeleton. AKT/PKB is constitutively active in many types of human cancer, and contributes to tumor progression by promoting angiogenesis and cell invasiveness. AKT is fully activated by phosphorylation of threonine 308 by PDK1 and serine 473 by PDK2. The reactivity of this antibody with AKT2 and AKT3 has not been tested. Synonyms: Protein Kinase B, RAC-alpha, EC 2.7.11.1, RAC-PK-alpha, PKB, C-AKT. |
| Synonyms | AKT, PKB, RAC, PRKBA, MGC99656, PKB-ALPHA, RAC-ALPHA, Akt, pkb, xAct, akt-1, v-akt, v-akt1, AKT1, AKT/PKB, D-Akt, DAKT1, DAKT1/PKB, DPKB, DRAC-PK, DRAC-PK66; DRAC-PK85, Dakt, PKB/AKT, PKB/dAKT, RacPK, dAKT/dPKB, dAkt/PKB, l(3)04226, l(3)89Bq, DmelCG4006, CG4006 |
Application Details
| Application Notes | For Western blotting, the recommended concentration is 1 g/mL . Positive Control: Positive Control: Human Jurkat cells, mouse 3T3-L1 cells, and rat PC-12 cells. Found in all human cell types so far analyzed. Found in the cytoplasm (and in the nucleus after activation by integrin-linked protein kinase 1). |
| Storage | Product should be stored at -20C. Aliquot to avoid freeze/thaw cycles |
| Restrictions | For Research Use only |
Alternatives
Alternatives for antigen "V-Akt Murine Thymoma Viral Oncogene Homolog 1 (AKT1)", type "Antibodies"
| Hosts | Rabbit (163), Mouse (59), Sheep (4), Chicken (1) |
| Reactivities | Human (214), Mouse (Murine) (121), Rat (Rattus) (112), Chicken (7), Dog (Canine) (4), Chimpanzee (2), Cow (Bovine) (2), Frog (1), Rabbit (1), Sheep (Ovine) (1) |
| Applications | Western Blotting (WB) (182), Immunohistochemistry (IHC) (64), Enzyme Immunoassay (EIA) (60), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)) (59), ELISA (54), Immunofluorescence (IF) (45), Immunoprecipitation (IP) (16), Immunohistochemistry (Frozen Sections) (IHC (fro)) (11), Dot Blot (Dot) (9), Flow Cytometry (FACS) (4), Immunocytochemistry (ICC) (2), ELISA (Detection) (1) |
| Conjugates | Biotin (2), APC (1) |
| Epitopes | pSer473 (21), pThr308 (14), pThr450 (5), pTyr315/316/312 (4), S129 (3), C-Term (2), N-Term (2), S246 (2), pS124 (2), pS473 (2), pThr308/309 (2), pY326 (2), N-Term G37 (1), S124 (1), S473 (1), pT308 (1) |
