Add to Basket
Order hotline:
 |
+1 404 474 4654 |
 |
+1 888 205 9894 (TF) |
V-Kit Hardy-Zuckerman 4 Feline Sarcoma Viral Oncogene Homolog (KIT) (pY936) antibody
| Antigen | V-Kit Hardy-Zuckerman 4 Feline Sarcoma Viral Oncogene Homolog (KIT) |
| Synonyms | PBT, SCFR, C-Kit, CD117, W, Bs, Fdc, Ssm, SCO1, SCO5, SOW3, c-KIT, Tr-kit, Gsfsco1, Gsfsco5, Gsfsow3, c-kit, kit-A, XKrk1, KIT, MGF, LOC100221238, C-KIT |
| Epitope |
 Alternatives pY936 |
| Host |
Alternatives Rabbit |
| Reactivity |
Alternatives Human |
| Application |
Alternatives Western Blotting (WB)
|
| Catalog no. | ABIN307101 |
| Quantity | 10 Miniblots |
| Price | 285.00 $ Plus shipping costs $35.00 |
| Shipping to |
|
| Availability | Ships within 5 to 7 Business Days |
Additional Information
| Alternative name | phospho c-Kit [pY936] |
| Swiss-Prot | P10721 |
| Isotype | IgG2b (Matching secondary antibodies) |
| Clone | Polyclonal |
| Description | C-Kit, also known as CD117 and stem cell factor receptor, is a 145 kDa transmembrane tyrosine kinase encoded by the c-Kit proto-oncogene. c-Kit acts to regulate a variety of biological responses including cell proliferation, apoptosis, chemotaxis and adhesion. Ligand binding to the extracellular domain leads to autophosphorylation on several tyrosine residues within the cytoplasmic domain, and activation. c-Kit mutations correlate with tumor growth and progression in a variety of cancers including mast cell disease, gastrointestinal stromal tumor, acute myeloid leukemia, Ewing sarcoma, and lung cancer. Phosphorylation at tyrosine 936 of c-Kit allows binding of Grb2 and activation of the Ras Raf ERK1&2 signaling pathway. Synonyms: EC 2.7.10.1, Proto-oncogene tyrosine-protein kinase Kit, CD117. |
Application Details
| Application Notes | For Western blotting applications, we recommend using the antibody at a 1:1000 dilution. |
| Storage | Product should be stored at -20C. Aliquot to avoid freeze/thaw cycles |
| Restrictions | For Research Use only |
Alternatives
Alternatives for antigen "V-Kit Hardy-Zuckerman 4 Feline Sarcoma Viral Oncogene Homolog (KIT)", type "Antibodies"
| Hosts | Rabbit (84), Mouse (53), Rat (38) |
| Reactivities | Human (117), Mouse (Murine) (59), Rat (Rattus) (18), Chicken (9), Dog (Canine) (6), Cow (Bovine) (5), Primate (4), Monkey (2), Pig (Porcine) (2) |
| Applications | Flow Cytometry (FACS) (70), Western Blotting (WB) (54), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)) (43), Enzyme Immunoassay (EIA) (24), Immunohistochemistry (IHC) (21), Immunohistochemistry (Frozen Sections) (IHC (fro)) (18), ELISA (12), Immunoprecipitation (IP) (12), Immunofluorescence (IF) (8), Dot Blot (Dot) (5), Immunocytochemistry (ICC) (4), ELISA (Detection) (1), Functional Studies (Func) (1), Neutralization (Neut) (1) |
| Conjugates | PE (14), FITC (12), Biotin (6), APC (2), APC,Cy7 (2), Cy5 (2), SPRD (2), RPE (1) |
| Epitopes | pTyr721 (10), C-Term (4), pTyr936 (4), N-Term (2), pTyr719 (2), Y721 (1), pS741 (1), pY703 (1), pY721 (1) |
