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Vav 3 Oncogene (VAV3) (pY173) antibody

Antigen

Vav 3 Oncogene (VAV3)
Synonyms FLJ40431, AA986410, MGC27838, A530094I06Rik, RGD1565941, VAV3, LOC100220994
Epitope

pY173
Host
Alternatives

Rabbit
Reactivity
Alternatives

Human, Mouse (Murine)
Application
Alternatives Western Blotting (WB)
Catalog no. ABIN307104
Quantity 10 Miniblots
Price 285.00 $   Plus shipping costs $35.00
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Availability Ships within 5 to 7 Business Days

Additional Information
Application Details Alternatives Secondary Antibodies back to top

Alternative name phospho Vav3 [pY173]
Swiss-Prot Q9UKW4
Isotype IgG  (Matching secondary antibodies)
Description Vav proteins belong to the guanidine nucleotide exchange factor family of proteins. These proteins couple receptors to Rho-GTPases. To date, three members of the Vav family have been identified in mammalian cells: Vav1, Vav2, and Vav3. Vav proteins contain multiple protein binding motifs and act as adaptor proteins linking cell surface receptors to downstream signaling proteins. Vav3 transcripts are ubiquitously expressed in wide variety of cell lines including hematopoietic cells, suggesting its role in lymphocyte development and antigen receptor mediated activation of NFAT and NF B. Vav3 is also involved in activating JNK, p21-activated kinase (PAK) and PLC , implicating a critical role in cytoskeletal rearrangement. Vav3 is inducibly tyrosine phosphorylated in response to stimulation of the epidermal growth factor (EGFR), platelet-derived growth factor (PDGFR) and T-cell receptors (TCR), enhancing its guanine nucleotide exchange factor activity in vitro. Tyrosine 173 is the regulatory phosphorylation site of Vav3.

Application Details
Alternatives Secondary Antibodies back to top

Application Notes Antibody can be used for Western blotting (1:1000 dilution). Positive Control: Cos7 cells overexpressing Vav3, +/- epidermal growth factor (EGF).
Storage Product should be stored at -70C. Aliquot to avoid freeze/thaw cycles
Restrictions For Research Use only

Alternatives
Application Details Secondary Antibodies back to top

Alternatives for antigen "Vav 3 Oncogene (VAV3)", type "Antibodies"
Hosts Rabbit (22), Goat (5)
Reactivities Human (25), Mouse (Murine) (20), Rat (Rattus) (19), Chicken (1), Cow (Bovine) (1)
Applications Flow Cytometry (FACS) (18), Immunofluorescence (IF) (18), Western Blotting (WB) (9), ELISA (4), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)) (3), Enzyme Immunoassay (EIA) (2), Immunohistochemistry (Formalin-fixed Sections) (IHC (f)) (2), Immunoprecipitation (IP) (2), Immunoelectron Microscopy (IEM) (1)
Conjugates Alexa Flour 488 (1), Alexa Fluor 350 (1), Alexa Fluor 488 (1), Alexa Fluor 555 (1), Alexa Fluor 647 (1), Biotin (1), Cy3 (1), Cy5 (1), Cy5.5 (1), Cy7 (1), FITC (1), Gold (1), HRP (1), PE (1), PE,Cy3 (1), PE,Cy5 (1), PE,Cy5.5 (1), PE,Cy7 (1), RBITC (1)