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Neural Precursor Cell Expressed, Developmentally Down-Regulated 8 (NEDD8) antibody

Antigen

Neural Precursor Cell Expressed, Developmentally Down-Regulated 8 (NEDD8)
Synonyms Nedd-8, FLJ43224, MGC104393, MGC125896, MGC125897, Rub1, MGC105320, CG10679, DmelCG10679, nedd8, ubiquitin, si:zc14a17.5, NEDD8, GB17785, LOC100009008
Clonality Polyclonal
Host
Alternatives

Rabbit
Reactivity
Alternatives

Human
Application
Alternatives Immunohistochemistry (IHC), ELISA
Catalog no. ABIN308181
Quantity 100µ  (Variants)
Price 329.16 $   Plus shipping costs $35.00
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Additional Information
Application Details Alternatives Secondary Antibodies Variants back to top

Immunogen A 14 amino acid synthetic peptide from the human NEDD8 conjugated to Dip. Tox. Produced in: NZ white rabbit.
Format Antiserum, Lyophilized
Description Ubiquitin-like protein which plays an important role in cell cycle control and embryogenesis. Covalent attachment to its substrates requires prior activation by the E1 complex UBE1C-APPBP1 and linkage to the E2 enzyme UBE2M. Attachment of NEDD8 to cullins activates their associated E3 ubiquitin ligase activity, and thus promotes polyubiquitination and proteasomal degradation of cyclins and other regulatory proteins
Specificity Confirmed by immunohistochemical analysis of human brain. Specific detection in neurons, glial inclusions and Lewy bodies.

Application Details
Alternatives Secondary Antibodies Variants back to top

Application Notes Immunohistochemistry and 1 site ELISA. Immunohistochemistry: Use at 1: 800 dilution. The end user should determine the optimal dilution.
Purity Whole Serum
Storage Long term - 70ºC dry Short term - 20ºC solution or 4ºC with appropriate antibacterial agent. Avoid repeated freezing and thawing. Glycerol (1:1) can be added for additional stability. Reconstitute with addition of 100µl of sterile water.
Restrictions For Research Use only

Alternatives
Application Details Secondary Antibodies Variants back to top

Alternatives for antigen "Neural Precursor Cell Expressed, Developmentally Down-Regulated 8 (NEDD8)", type "Antibodies"
Hosts Rabbit (35), Sheep (2), Mouse (1)
Reactivities Human (32), Rat (Rattus) (24), Mouse (Murine) (23), Yeast (Saccharomyces Cerevisiae) (2)
Applications Western Blotting (WB) (20), Immunofluorescence (IF) (19), Flow Cytometry (FACS) (18), ELISA (9), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)) (8), Enzyme Immunoassay (EIA) (6), Immunohistochemistry (Frozen Sections) (IHC (fro)) (4), Immunohistochemistry (IHC) (4), Immunoprecipitation (IP) (4), Immunohistochemistry (Formalin-fixed Sections) (IHC (f)) (2), Immunocytochemistry (ICC) (1), Immunoelectron Microscopy (IEM) (1)
Conjugates Alexa Flour 488 (1), Alexa Fluor 350 (1), Alexa Fluor 488 (1), Alexa Fluor 555 (1), Alexa Fluor 647 (1), Biotin (1), Cy3 (1), Cy5 (1), Cy5.5 (1), Cy7 (1), FITC (1), Gold (1), HRP (1), PE (1), PE,Cy3 (1), PE,Cy5 (1), PE,Cy5.5 (1), PE,Cy7 (1), RBITC (1)
Epitopes N-Term (6), C-Term (2)