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DNA (Cytosine-5)-Methyltransferase 1 (DNMT1) antibody

Antigen

DNA (Cytosine-5)-Methyltransferase 1 (DNMT1)

Synonyms
AIM, DNMT, MCMT, CXXC9, FLJ16293, MGC104992, Dnmt, Met1, Cxxc9, MTase, Met-1, Dnmt1o, MommeD2, mta, cb983, dmnt1, cb1075, fb05h01, wu:fb05h01, DDM2, DECREASED DNA METHYLATION 2, DMT01, DMT1, DNA METHY ... show more
Clonality Polyclonal
Host
Reactivity
Alternatives

Human

Conjugate
Alternatives Un-conjugated
Application
Alternatives ELISA, Western Blotting (WB)
1 reference available
Catalog no. ABIN308397
Quantity 100 ug  (Variants)
Price 374.27 $   Plus shipping costs $45.00
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Additional Information

Alternative name DNMT1
Gene ID 1786, 13433 (mouse), 84350 (rat)
Immunogen C-RFESPPKTQPTEDN
Description All names and symbols: DNMT1, DNA (cytosine-5-)-methyltransferase 1, CXXC9, DNMT, FLJ16293, MCMT, MGC104992, DNA methyltransferase 1. Official Symbol: DNMT1. RefSeq number(s): NP_001370.1
Specificity Human, Mouse, Rat, Dog, Cow, Pig
Synonyms AIM, DNMT, MCMT, CXXC9, FLJ16293, MGC104992, Dnmt, Met1, Cxxc9, MTase, Met-1, Dnmt1o, MommeD2, mta, cb983, dmnt1, cb1075, fb05h01, wu:fb05h01, DDM2, DECREASED DNA METHYLATION 2, DMT01, DMT1, DNA METHYLTRANSFERASE, DNA METHYLTRANSFERASE 01, DNA METHYLTRANSFERASE 1, MET1, MET2, methyltransferase 1, METHYLTRANSFERASE 2, METHYLTRANSFERASE I, METI

Application Details

Application Notes Peptide ELISA: antibody detection limit dilution 1:32,000. Western Blot: Approx 170kDa band observed in lysates of cell line Jurkat (calculated MW of 183kDa according to NP_001370.1). Recommended concentration: 0.5-1.5µg/ml.
Purification Purified from goat serum by ammonium sulphate precipitation followed by antigen affinity chromatography using the immunizing peptide.
Buffer Supplied at 0.5 mg/ml in Tris saline, 0.02% sodium azide, pH7.3 with 0.5% bovine serum albumin.
Storage Aliquot and store at -20°C. Minimize freezing and thawing.
Research Area DNA/RNA
Restrictions For Research Use only

Publications

Dion, Lin, Hubert et al.: "Dnmt1 deficiency promotes CAG repeat expansion in the mouse germline." in: Human molecular genetics, Vol. 17, Issue 9, pp. 1306-17, 2008 (PubMed).

Alternatives

Alternatives for antigen "DNA (Cytosine-5)-Methyltransferase 1 (DNMT1)", type "Antibodies"
Hosts Rabbit (81), Mouse (9), Goat (6), Chicken (5), Rat (1)
Reactivities Human (96), Dog (Canine) (41), Mouse (Murine) (40), Pig (Porcine) (36), Cow (Bovine) (32), Rat (Rattus) (28), Sheep (Ovine) (28), Chicken (23), Horse (Equine) (23), Zebrafish (3), Zebrafish (Danio rerio) (2)
Applications Western Blotting (WB) (47), Immunofluorescence (IF) (40), ELISA (35), Immunoprecipitation (IP) (17), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)) (16), Dot Blot (Dot) (6), Immunohistochemistry (IHC) (6), Chromatin Immunoprecipitation (ChiP) (3), Immunohistochemistry (Formalin-fixed Sections) (IHC (f)) (3), Chromatin Immunoprecipitation (ChIP) (2), Immunocytochemistry (ICC) (2), Flow Cytometry (FACS) (1), Immunoelectron Microscopy (IEM) (1)
Conjugates Alexa Fluor 350 (5), Alexa Fluor 488 (5), Alexa Fluor 555 (5), Alexa Fluor 647 (5), PE,Cy5.5 (5), Biotin (1), Cy3 (1), Cy5 (1), Cy5.5 (1), Cy7 (1), FITC (1), Gold (1), HRP (1), PE (1), PE,Cy3 (1), PE,Cy5 (1), PE,Cy7 (1)
Epitopes pTyr399 (7), pSer153 (5), pSer730 (5), AA 637-650 (4), pTyr985 (4), N-Term (3), pTyr405 (3), AA 177-550 (2), Ser1105 (2), pSer154 (2), pSer714 (2), pTyr969 (2), AA 1603-1616 (1), C-Term (1), C-Term,Ser1602 (1), Internal Region (1), pSer509 (1), pSer671 (1)