Chemokine (C-C Motif) Ligand 11 (CCL11) antibody

Antigen: Chemokine (C-C Motif) Ligand 11 (CCL11)

Synonyms: Scya11, CCL11, MGC137967, SCYA11, Eotaxin, Ccl11, CACH2C, CACH2, CACN2, CCHL1A1, Cacna1c, CACNL1A1, MGC22554

Clonality: Polyclonal

Host: Goat

Application: ELISA

Catalog no.: ABIN308449

Additional Information

Alternative name: eotaxin

Gene ID: 6356

Immunogen: C-QDSMKYLDQKSPTPK

Format: Affinity-purified

Description: All names and symbols: CCL11, chemokine (C-C motif) ligand 11, MGC22554, SCYA11, eosinophil chemotactic protein, eotaxin, small inducible cytokine A11, small inducible cytokine subfamily A (Cys-Cys), member 11 (eotaxin). Official Symbol: CCL11. RefSeq number(s): NP_002977.1

Specificity: Human

Application Details

Application Notes: Peptide ELISA: antibody detection limit dilution 1:2,000. Western Blot: No specific signals and low background in Human Colon, Duodenum, Ileum and Lung lysates - our routinely used western blotting protocol does not allow detection of proteins as small as the ligand derived from its precursor or the orecusor itself with calculated size of 10.7kDa according to NP_002977.1. Therefore we cannot recommend an optimal concentration and the product is investigative grade. We would appreciate any feedback from people in the field - have any assay results been reported with other antibodies?

Purification: Purified from goat serum by ammonium sulphate precipitation followed by antigen affinity chromatography using the immunizing peptide.

Buffer: Supplied at 0.5 mg/ml in Tris saline, 0.02% sodium azide, pH7.3 with 0.5% bovine serum albumin.

Storage: Aliquot and store at -20°C. Minimize freezing and thawing.

Restrictions: For Research Use only

Publications

Publications: Issa, Sorrentino, Sukkar et al.: "Differential regulation of CCL-11/eotaxin-1 and CXCL-8/IL-8 by gram-positive and gram-negative bacteria in human airway smooth muscle cells." in: Respiratory research, Vol. 9, pp. 30, 2008 (PubMed).