HOXC11 antibody (Middle Region)

Catalog No. ABIN309664

Product Details anti-HOXC11 Antibody

Target: HOXC11 (Homeobox C11 (HOXC11))

Binding Specificity: Middle Region

Reactivity: Human, Mouse, Rat, Guinea Pig, Horse, Cow, Rabbit, Dog

Host: Rabbit

Clonality: Polyclonal

Conjugate: This HOXC11 antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (IHC)

Sequence: DRFFDNAYCG GGDPPAEPPC SGKGEAKGEP EAPPASGLAS RAEAGAEAEA

Predicted Reactivity: Cow: 100%, Dog: 92%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 100%, Rabbit: 100%, Rat: 100%

Characteristics: This is a rabbit polyclonal antibody against HOXC11. It was validated on Western Blot using a cell lysate as a positive control.

Purification: Protein A purified

Immunogen: The immunogen is a synthetic peptide directed towards the middle region of human HOXC11

Application Details

Application Notes: Optimal working dilutions should be determined experimentally by the investigator.

Comment:

Antigen size: 304 AA

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freeze-thaw cycles.

Storage: -20 °C

Storage Comment: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Target Details for HOXC11

Target: HOXC11 (Homeobox C11 (HOXC11))

Alternative Name: HOXC11 (HOXC11 Products)

Synonyms: HOX3H antibody, Hox-3.7 antibody, HOXC11 antibody, RGD1305450 antibody, homeobox C11 antibody, HOXC11 antibody, Hoxc11 antibody

Background: HOXC11 belongs to the homeobox family. The homeobox family is a highly conserved family of transcription factors that play an important role in morphogenesis in all multicellular organisms. HOXC11 is one of several homeobox HOXC proteins. HOXC11 binds to a promoter element of the lactase-phlorizin hydrolase. It may also play a role in early intestinal development.This gene belongs to the homeobox family of genes. The homeobox genes encode a highly conserved family of transcription factors that play an important role in morphogenesis in all multicellular organisms. Mammals possess four similar homeobox gene clusters, HOXA, HOXB, HOXC and HOXD, which are located on different chromosomes and consist of 9 to 11 genes arranged in tandem. This gene is one of several homeobox HOXC genes located in a cluster on chromosome 12. The product of this gene binds to a promoter element of the lactase-phlorizin hydrolase. It also may play a role in early intestinal development. An alternatively spliced variant encoding a shorter isoform has been described but its full-length nature has not been determined.
Alias Symbols: HOX3H, MGC4906
Protein Interaction Partner: HTT, ELAVL1, CD2AP, SOX8, TBX21, GTF2A1L, HDAC5, STAT3, SP1, MEIS1, SMAD3, IRF4, GTF2H1,
Protein Size: 304

Molecular Weight: 34 kDa

Gene ID: 3227

NCBI Accession: NM_014212, NP_055027

UniProt: O43248