Homeobox C11 (HOXC11) (Middle Region) antibody

Details for Product No. ABIN309664
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Antigen
Synonyms HOXC11, HOX3H, Hox-3.7, RGD1305450
Epitope
Middle Region
(8), (7), (2), (2), (1), (1)
Reactivity
Mouse (Murine), Rat (Rattus), Cow (Bovine), Dog (Canine), Human
(25), (12), (1), (1), (1), (1)
Host
Rabbit
(19), (15)
Clonality
Polyclonal
Conjugate
Un-conjugated
(1), (1), (1), (1), (1), (1)
Application
Immunohistochemistry (IHC), Western Blotting (WB)
(31), (15), (15), (6), (5), (4), (2)
Pubmed 1 reference available
Quantity 100 µg
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Catalog No. ABIN309664
229.00 $
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Immunogen Synthetic peptide directed towards the middle region of human HOXC11
Sequence DRFFDNAYCG GGDPPAEPPC SGKGEAKGEP EAPPASGLAS RAEAGAEAEA
Predicted Reactivity Bovine : 100 %, Mouse : 100 %, Rabbit : 100 %, Rat : 100 %, Dog : 90 %
Characteristics This is a rabbit polyclonal antibody against HOXC11. It was validated on Western Blot using a cell lysate as a positive control.
Purification Protein A purified
Alternative Name HOXC11
Background HOXC11 belongs to the homeobox family. The homeobox family is a highly conserved family of transcription factors that play an important role in morphogenesis in all multicellular organisms. HOXC11 is one of several homeobox HOXC proteins. HOXC11 binds to a promoter element of the lactase-phlorizin hydrolase. It may also play a role in early intestinal development.This gene belongs to the homeobox family of genes. The homeobox genes encode a highly conserved family of transcription factors that play an important role in morphogenesis in all multicellular organisms. Mammals possess four similar homeobox gene clusters, HOXA, HOXB, HOXC and HOXD, which are located on different chromosomes and consist of 9 to 11 genes arranged in tandem. This gene is one of several homeobox HOXC genes located in a cluster on chromosome 12. The product of this gene binds to a promoter element of the lactase-phlorizin hydrolase. It also may play a role in early intestinal development. An alternatively spliced variant encoding a shorter isoform has been described but its full-length nature has not been determined.
Molecular Weight 34 kDa
Gene ID 3227
NCBI Accession NM_014212, NP_055027
UniProt O43248
Research Area Chromatin and Nuclear Signaling, Transcription Factors
Application Notes Optimal working dilutions should be determined experimentally by the investigator.
Comment

Antigen size: 304 AA

Restrictions For Research Use only
Format Lyophilized
Reconstitution Add 100 µL of distilled water.
Concentration 1 mg/mL
Buffer PBS buffer with 2 % sucrose
Handling Advice Avoid repeated freeze-thaw cycles.
Storage -20 °C
Storage Comment For longer periods of storage, store at -20 °C
Background publications Kosaki, Kosaki, Suzuki et al.: "Complete mutation analysis panel of the 39 human HOX genes." in: Teratology, Vol. 65, Issue 2, pp. 50-62, 2002 (PubMed).

Validation Images
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