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Antibodies
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anti-Sodium Channel, Voltage-Gated, Type I, beta (SCN1B) antibody
Sodium Channel, Voltage-Gated, Type I, beta (SCN1B) antibody
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| Synonyms |
GEFSP1 |
| Clonality |
Polyclonal |
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Host
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Reactivity
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 Alternatives Cow (Bovine), Dog (Canine), Human, Mouse (Murine), Rabbit, Rat (Rattus)
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Application
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| Catalog no. |
ABIN309761 |
| Quantity |
50 µg |
| Price |
Product not available in this region.
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| Shipping to |
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Alternative name
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SCN1B
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Description
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Voltage-gated sodium channels are essential for the generation and propagation of action potentials in striated muscle and neuronal tissues. Biochemically, they consist of a large alpha subunit and 1 or 2 smaller beta subunits, such as SCN1B. The alpha subunit alone can exhibit all the functional attributes of a voltage-gated Na+ channel, but requires a beta-1 subunit for normal inactivation kinetics.Voltage-gated sodium channels are essential for the generation and propagation of action potentials in striated muscle and neuronal tissues. Biochemically, they consist of a large alpha subunit and 1 or 2 smaller beta subunits, such as SCN1B. The alpha subunit alone can exhibit all the functional attributes of a voltage-gated Na+ channel, but requires a beta-1 subunit for normal inactivation kinetics.[supplied by OMIM]. Keywords: SCN1B, GEFSP1, NP_001028
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Application Notes
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ELISA titre: 1:62500 . Western Blotting: Suggested dilution at 1 ug/ml in 5% skim milk / PBS buffer, and HRP conjugated anti-Rabbit IgG should be diluted in 1: 50,000 - 100,000 as second antibody.
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Research Area
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Signaling, Metabolism
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Restrictions
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For Research Use only
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Publications
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Selmer, Egeland, Solaas et al.: "Genetic screening of Scandinavian families with febrile seizures and epilepsy or GEFS+." in: Acta neurologica Scandinavica, Vol. 117, Issue 4, pp. 289-92, 2008 (PubMed).
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Alternatives for antigen "Sodium Channel, Voltage-Gated, Type I, beta (SCN1B)", type "Antibodies"
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Hosts
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Rabbit (24)
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Reactivities
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Human (23), Mouse (Murine) (20), Rat (Rattus) (20), Cow (Bovine) (2), Dog (Canine) (2), Horse (Equine) (2), Pig (Porcine) (2)
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Applications
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Flow Cytometry (FACS) (18), Immunofluorescence (IF) (18), Western Blotting (WB) (7), ELISA (4), Immunohistochemistry (Formalin-fixed Sections) (IHC (f)) (2), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)) (2), Immunoprecipitation (IP) (2), Immunoelectron Microscopy (IEM) (1)
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Conjugates
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Alexa Flour 488 (1), Alexa Fluor 350 (1), Alexa Fluor 488 (1), Alexa Fluor 555 (1), Alexa Fluor 647 (1), Biotin (1), Cy3 (1), Cy5 (1), Cy5.5 (1), Cy7 (1), FITC (1), Gold (1), HRP (1), PE (1), PE,Cy3 (1), PE,Cy5 (1), PE,Cy5.5 (1), PE,Cy7 (1), RBITC (1)
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