Fused in Sarcoma (FUS) (N-Term) antibody

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Antigen
Synonyms ALS6, ETM4, FUS1, HNRNPP2, POMP75, TLS, D430004D17Rik, D930039C12Rik, Fus1, Tls, FUS/TLS
Epitope
N-Term
(18), (13), (13), (5), (4), (3), (2), (2), (2), (2), (2), (1), (1), (1)
Reactivity
Chicken, Cow (Bovine), Human, Mouse (Murine), Rat (Rattus)
(98), (44), (24), (1)
Host
Rabbit
(98), (3), (1)
Clonality
Polyclonal
Conjugate
Un-conjugated
(10), (10), (9), (2), (2), (2), (1), (1), (1), (1), (1), (1), (1), (1), (1)
Application
Immunohistochemistry (IHC), Western Blotting (WB)
(76), (52), (38), (26), (18), (16), (15), (11), (6), (2), (1), (1)
Pubmed 1 reference available
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Quantity 50 μg
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Immunogen Synthetic peptide directed towards the N terminal of human FUS
Blocking Peptide Blocking peptide for this product available: FUS (Fusion (Involved in T (1216) in Malignant Liposarcoma)) peptide (ABIN977142)
Sequence MASNDYTQQA TQSYGAYPTQ PGQGYSQQSS QPYGQQSYSG YSQSTDTSGY
Predicted Reactivity Human : 100 %, Mouse : 100 %, Bovine : 90 %, Dog : 90 %, Pig : 90 %, Rabbit : 90 %, Rat : 90 %, Chicken : 70 %
Characteristics This is a rabbit polyclonal antibody against FUS. It was validated on Western Blot and immunohistochemistry.
Purification Affinity Purified
Alternative Name FUS (FUS Antibody Abstract)
Background FUS binds both single-stranded and double-stranded DNA and promotes ATP-independent annealing of complementary single-stranded DNAs and D-loop formation in superhelical double-stranded DNA. FUS may play a role in maintenance of genomic integrity.
Molecular Weight 29 kDa
Gene ID 2521
NCBI Accession NM_001010850, NP_001010850
Application Notes Optimal working dilutions should be determined experimentally by the investigator.
Comment

Antigen size: 263 AA

Restrictions For Research Use only
Format Lyophilized
Reconstitution Add 50 µL of distilled water.
Concentration 1 mg/mL
Buffer PBS buffer with 2 % sucrose
Handling Advice Avoid repeated freeze-thaw cycles.
Storage -20 °C
Storage Comment For longer periods of storage, store at -20 °C
Supplier Images
Western Blotting (WB) image for anti-Fused in Sarcoma (FUS) (N-Term) antibody (ABIN310014) WB Suggested Anti-FUS Antibody Titration: 0.2-1 ug/ml
Positive Control: ...
Immunohistochemistry (IHC) image for anti-Fused in Sarcoma (FUS) (N-Term) antibody (ABIN310014) anti-Fused in Sarcoma (FUS) (N-Term) antibody (Image 2)
Immunohistochemistry (IHC) image for anti-Fused in Sarcoma (FUS) (N-Term) antibody (ABIN310014) anti-Fused in Sarcoma (FUS) (N-Term) antibody (Image 3)
Western Blotting (WB) image for anti-Fused in Sarcoma (FUS) (N-Term) antibody (ABIN310014) WB Suggested Anti-FUS Antibody
Positive Control: Lane 1:41 µg mouse brain cyto...
Background publications Sato, Idogawa, Honda et al.: "Beta-catenin interacts with the FUS proto-oncogene product and regulates pre-mRNA splicing." in: Gastroenterology, Vol. 129, Issue 4, pp. 1225-36, 2005 (PubMed).

Catalog No. ABIN310014
$289.00
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