Fused in Sarcoma (FUS) (N-Term) antibody

Details for Product No. ABIN310014
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Antigen
Synonyms ALS6, ETM4, FUS1, HNRNPP2, POMP75, TLS, D430004D17Rik, D930039C12Rik, Fus1, Tls, FUS/TLS
Epitope
N-Term
(7), (7), (5), (5), (5), (2), (2), (1), (1), (1)
Reactivity
Mouse (Murine), Rat (Rattus), Cow (Bovine), Human, Chicken
(71), (32), (17), (17), (12), (12), (1)
Host
Rabbit
(71), (1)
Clonality
Polyclonal
Conjugate
Un-conjugated
(7), (7), (6), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1)
Application
Immunohistochemistry (IHC), Western Blotting (WB)
(60), (30), (24), (21), (17), (12), (10), (10), (7), (2), (1), (1)
Pubmed 1 reference available
Quantity 50 μg
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Catalog No. ABIN310014
289.00 $
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Immunogen Synthetic peptide directed towards the N terminal of human FUS
Sequence MASNDYTQQA TQSYGAYPTQ PGQGYSQQSS QPYGQQSYSG YSQSTDTSGY
Predicted Reactivity Human : 100 %, Mouse : 100 %, Bovine : 90 %, Dog : 90 %, Pig : 90 %, Rabbit : 90 %, Rat : 90 %, Chicken : 70 %
Characteristics This is a rabbit polyclonal antibody against FUS. It was validated on Western Blot and immunohistochemistry.
Purification Affinity Purified
Alternative Name FUS
Background FUS binds both single-stranded and double-stranded DNA and promotes ATP-independent annealing of complementary single-stranded DNAs and D-loop formation in superhelical double-stranded DNA. FUS may play a role in maintenance of genomic integrity.
Molecular Weight 29 kDa
Gene ID 2521
NCBI Accession NM_001010850, NP_001010850
Application Notes Optimal working dilutions should be determined experimentally by the investigator.
Comment

Antigen size: 263 AA

Restrictions For Research Use only
Format Lyophilized
Reconstitution Add 50 µL of distilled water.
Concentration 1 mg/mL
Buffer PBS buffer with 2 % sucrose
Handling Advice Avoid repeated freeze-thaw cycles.
Storage -20 °C
Storage Comment For longer periods of storage, store at -20 °C
Supplier Images
anti-Fused in Sarcoma (FUS) (N-Term) antibody WB Suggested Anti-FUS Antibody Titration: 0.2-1 ug/ml
Positive Control: HepG2 cell lysate
anti-Fused in Sarcoma (FUS) (N-Term) antibody (2) anti-Fused in Sarcoma (FUS) (N-Term) antibody (Image 2)
anti-Fused in Sarcoma (FUS) (N-Term) antibody (3) anti-Fused in Sarcoma (FUS) (N-Term) antibody (Image 3)
anti-Fused in Sarcoma (FUS) (N-Term) antibody (4) WB Suggested Anti-FUS Antibody
Positive Control: Lane 1:41 µg mouse brain cytoplasm Lane 2: uug mouse brain nucleus
Primary Antibody Dilution: 1:u000
Secondary Antibody: Anti rabbit - IR-dyeSecondry
Antibody Dilution: 1:u0,000
Submitted by: Anonymous
Background publications Sato, Idogawa, Honda et al.: "Beta-catenin interacts with the FUS proto-oncogene product and regulates pre-mRNA splicing." in: Gastroenterology, Vol. 129, Issue 4, pp. 1225-36, 2005 (PubMed).

Validation Images
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