anti-FTCD antibody (Formiminotransferase Cyclodeaminase) (N-Term)

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Antigen
Epitope
N-Term
(10), (4), (3), (3), (2), (2), (1), (1), (1)
Reactivity
Chicken, Dog (Canine), Human, Mouse (Murine), Pig (Porcine), Rat (Rattus), Zebrafish (Danio rerio)
(44), (14), (8), (6), (3), (3), (2), (2), (1)
Host
Rabbit
(21), (13), (10)
Clonality
Polyclonal
Application
Immunohistochemistry (IHC), Western Blotting (WB)
(40), (21), (17), (6), (5), (3), (2), (1), (1), (1)
Pubmed 2 references available
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Quantity 100 μg
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Immunogen Synthetic peptide directed towards the N terminal of human FTCD
Sequence FSEGKNQEVI DAISGAITQT PGCVLLDVDA GPSTNRTVYT FVGPPECVVE
Predicted Reactivity Bovine : 100 %, Dog : 100 %, Guinea pig : 100 %, Horse : 100 %, Human : 100 %, Mouse : 100 %, Rabbit : 100 %, Rat : 100 %, Chicken : 90 %, Pig : 90 %, Zebrafish : 80 %
Characteristics This is a rabbit polyclonal antibody against FTCD. It was validated on Western Blot and immunohistochemistry.
Purification Protein A purified
Alternative Name FTCD (FTCD Antibody Abstract)
Background FTCD is a bifunctional enzyme that channels 1-carbon units from formiminoglutamate, a metabolite of the histidine degradation pathway, to the folate pool.FTCD is a bifunctional enzyme that channels 1-carbon units from formiminoglutamate, a metabolite of the histidine degradation pathway, to the folate pool.
Molecular Weight 60 kDa
Gene ID 10841
NCBI Accession NM_006657, NP_006648
UniProt O95954
Application Notes Optimal working dilutions should be determined experimentally by the investigator.
Comment

Antigen size: 541 AA

Restrictions For Research Use only
Format Lyophilized
Reconstitution Add 100 µL of distilled water.
Concentration 1 mg/mL
Buffer PBS buffer with 2 % sucrose
Handling Advice Avoid repeated freeze-thaw cycles.
Storage -20 °C
Storage Comment For longer periods of storage, store at -20 °C
Supplier Images
Western Blotting (WB) image for anti-FTCD antibody (Formiminotransferase Cyclodeaminase) (N-Term) (ABIN310177) anti-Formiminotransferase Cyclodeaminase (FTCD) (N-Term) antibody
Immunohistochemistry (IHC) image for anti-FTCD antibody (Formiminotransferase Cyclodeaminase) (N-Term) (ABIN310177) anti-Formiminotransferase Cyclodeaminase (FTCD) (N-Term) antibody (Image 2)
Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)) image for anti-FTCD antibody (Formiminotransferase Cyclodeaminase) (N-Term) (ABIN310177) Rabbit Anti-FTCD Antibody ,Paraffin Embedded Tissue: Human Skin
Cellular Data:...
Product cited in: Vermeire, Brokx, Van de Heyning et al.: "Bilateral cochlear implantation in children." in: International journal of pediatric otorhinolaryngology, Vol. 67, Issue 1, pp. 67-70, 2003 (PubMed).

Background publications Hilton, Christensen, Watkins et al.: "The molecular basis of glutamate formiminotransferase deficiency." in: Human mutation, Vol. 22, Issue 1, pp. 67-73, 2003 (PubMed).