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DHODH antibody (C-Term)

DHODH Reactivity: Human, Mouse, Rat, Dog, Zebrafish (Danio rerio), Horse, Cow, Rabbit, Guinea Pig, Saccharomyces cerevisiae WB, IHC Host: Rabbit Polyclonal unconjugated
Catalog No. ABIN310258
  • Target See all DHODH Antibodies
    DHODH (Dihydroorotate Dehydrogenase (DHODH))
    Binding Specificity
    • 9
    • 7
    • 6
    • 6
    • 5
    • 3
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    C-Term
    Reactivity
    • 45
    • 14
    • 13
    • 10
    • 9
    • 8
    • 6
    • 6
    • 5
    • 5
    • 4
    • 4
    • 4
    • 3
    • 1
    • 1
    Human, Mouse, Rat, Dog, Zebrafish (Danio rerio), Horse, Cow, Rabbit, Guinea Pig, Saccharomyces cerevisiae
    Host
    • 42
    • 3
    Rabbit
    Clonality
    • 43
    • 2
    Polyclonal
    Conjugate
    • 31
    • 4
    • 3
    • 3
    • 2
    • 2
    This DHODH antibody is un-conjugated
    Application
    • 39
    • 27
    • 15
    • 6
    • 3
    • 3
    • 2
    • 1
    Western Blotting (WB), Immunohistochemistry (IHC)
    Sequence
    GGLSGKPLRD LSTQTIREMY ALTQGRVPII GVGGVSSGQD ALEKIRAGAS
    Predicted Reactivity
    Cow: 100%, Dog: 100%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 100%, Rabbit: 100%, Rat: 100%, Yeast: 91%, Zebrafish: 79%
    Characteristics
    This is a rabbit polyclonal antibody against DHODH. It was validated on Western Blot using a cell lysate as a positive control.
    Purification
    Affinity Purified
    Immunogen
    The immunogen is a synthetic peptide directed towards the C terminal region of human DHODH
    Top Product
    Discover our top product DHODH Primary Antibody
  • Application Notes
    Optimal working dilutions should be determined experimentally by the investigator.
    Comment

    Antigen size: 395 AA

    Restrictions
    For Research Use only
  • Format
    Liquid
    Concentration
    Lot specific
    Buffer
    Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
    Preservative
    Sodium azide
    Precaution of Use
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Handling Advice
    Avoid repeated freeze-thaw cycles.
    Storage
    -20 °C
    Storage Comment
    For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
  • Lazrek, Goffard, Schanen, Karquel, Bocket, Lion, Devaux, Hedouin, Gosset, Hober: "Detection of hepatitis C virus antibodies and RNA among medicolegal autopsy cases in Northern France." in: Diagnostic microbiology and infectious disease, Vol. 55, Issue 1, pp. 55-8, (2006) (PubMed).

  • Target
    DHODH (Dihydroorotate Dehydrogenase (DHODH))
    Alternative Name
    DHODH (DHODH Products)
    Synonyms
    DHOdehase antibody, POADS antibody, URA1 antibody, 2810417D19Rik antibody, AI834883 antibody, DDBDRAFT_0167009 antibody, DDBDRAFT_0185217 antibody, DDB_0167009 antibody, DDB_0185217 antibody, DHOD antibody, DHODase antibody, XFHB_12025 antibody, dhodh antibody, dihydroorotate dehydrogenase (quinone) antibody, dihydroorotate dehydrogenase antibody, dihydroorotate dehydrogenase (quinone) L homeolog antibody, DHODH antibody, Dhodh antibody, pyrD antibody, pyr4 antibody, Mrub_0263 antibody, Arnit_2124 antibody, Trad_2703 antibody, Ftrac_1484 antibody, Ndas_0799 antibody, Mesil_1876 antibody, Slip_0841 antibody, Spirs_1436 antibody, XFHB_RS12780 antibody, dhodh.L antibody
    Background
    DHODH catalyzes the fourth enzymatic step, the ubiquinone-mediated oxidation of dihydroorotate to orotate, in de novo pyrimidine biosynthesis. This protein is a mitochondrial protein located on the outer surface of the inner mitochondrial membrane.The protein encoded by this gene catalyzes the fourth enzymatic step, the ubiquinone-mediated oxidation of dihydroorotate to orotate, in de novo pyrimidine biosynthesis. This protein is a mitochondrial protein located on the outer surface of the inner mitochondrial membrane. Alternatively spliced transcript variants encoding different isoforms have been found for this gene.
    Alias Symbols: DHOdehase, URA1, POADS
    Protein Interaction Partner: UBC, TMED10, MT2A, FKBP8, SSBP1, SDHA, PLP2, OGDH, NDUFS8, HNRNPM, ILF3, CYC1,
    Protein Size: 395
    Molecular Weight
    43 kDa
    Gene ID
    1723
    NCBI Accession
    NM_001361, NP_001352
    UniProt
    Q02127
    Pathways
    Ribonucleoside Biosynthetic Process, Protein targeting to Nucleus
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