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CES2 antibody (C-Term)

CES2 Reactivity: Human, Mouse, Rat, Dog, Guinea Pig WB, IHC Host: Rabbit Polyclonal unconjugated
Catalog No. ABIN310292
  • Target See all CES2 Antibodies
    CES2 (Carboxylesterase 2 (CES2))
    Binding Specificity
    • 7
    • 7
    • 6
    • 6
    • 4
    • 3
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    C-Term
    Reactivity
    • 46
    • 9
    • 3
    • 3
    • 1
    • 1
    Human, Mouse, Rat, Dog, Guinea Pig
    Host
    • 40
    • 7
    • 3
    • 1
    Rabbit
    Clonality
    • 47
    • 4
    Polyclonal
    Conjugate
    • 34
    • 3
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This CES2 antibody is un-conjugated
    Application
    • 42
    • 26
    • 24
    • 12
    • 9
    • 7
    • 5
    • 4
    • 1
    • 1
    Western Blotting (WB), Immunohistochemistry (IHC)
    Sequence
    HWPLFDQEEQ YLQLNLQPAV GRALKAHRLQ FWKKALPQKI QELEEPEERH
    Predicted Reactivity
    Dog: 83%, Guinea Pig: 83%, Human: 100%, Mouse: 83%, Rat: 83%
    Characteristics
    This is a rabbit polyclonal antibody against CES2. It was validated on Western Blot using a cell lysate as a positive control.
    Purification
    Affinity Purified
    Immunogen
    The immunogen is a synthetic peptide directed towards the C terminal region of human CES2
    Top Product
    Discover our top product CES2 Primary Antibody
  • Application Notes
    Optimal working dilutions should be determined experimentally by the investigator.
    Comment

    Antigen size: 623 AA

    Restrictions
    For Research Use only
  • Format
    Liquid
    Concentration
    Lot specific
    Buffer
    Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
    Preservative
    Sodium azide
    Precaution of Use
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Handling Advice
    Avoid repeated freeze-thaw cycles.
    Storage
    -20 °C
    Storage Comment
    For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
  • Lazrek, Goffard, Schanen, Karquel, Bocket, Lion, Devaux, Hedouin, Gosset, Hober: "Detection of hepatitis C virus antibodies and RNA among medicolegal autopsy cases in Northern France." in: Diagnostic microbiology and infectious disease, Vol. 55, Issue 1, pp. 55-8, (2006) (PubMed).

  • Target
    CES2 (Carboxylesterase 2 (CES2))
    Alternative Name
    CES2 (CES2 Products)
    Synonyms
    CE-2 antibody, CES2A1 antibody, PCE-2 antibody, iCE antibody, Ces2 antibody, im:6908784 antibody, si:dkey-38l12.2 antibody, zgc:153863 antibody, ce-2 antibody, ces2a1 antibody, pce-2 antibody, carboxylesterase 2 antibody, liver carboxylesterase 2 antibody, cocaine esterase antibody, carboxylesterase 2 (intestine, liver) antibody, CES2 antibody, Ces2 antibody, LOC100343300 antibody, LOC100734360 antibody, ces2 antibody
    Background
    Carboxylesterase 2 is a member of a large multigene family. The enzymes are responsible for the hydrolysis of ester- and amide-bond-containing drugs such as cocaine and heroin. They also hydrolize long-chain fatty acid esters and thioesters. The specific function of this enzyme has not yet been determined, however, it is speculated that carboxylesterases may play a role in lipid metabolism and/or the blood-brain barrier system.Carboxylesterase 2 is a member of a large multigene family. The enzymes encoded by these genes are responsible for the hydrolysis of ester- and amide-bond-containing drugs such as cocaine and heroin. They also hydrolize long-chain fatty acid esters and thioesters. The specific function of this enzyme has not yet been determined, however, it is speculated that carboxylesterases may play a role in lipid metabolism and/or the blood-brain barrier system. Two alternatively spliced transcript variants encoding distinct isoforms have been found for this gene.
    Alias Symbols: CE-2, iCE, PCE-2, CES2A1
    Protein Size: 623
    Molecular Weight
    69 kDa
    Gene ID
    8824
    NCBI Accession
    NM_003869, NP_003860
    UniProt
    O00748
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