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Details for Product No. ABIN310301

RAD23 Homolog A (S. Cerevisiae) (RAD23A) (N-Term) antibody

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Antigen
Synonyms HHR23A, HR23A, mHR23A, AL024030, 2310040P19Rik, rad23a, wu:fe11h06, zgc:92001, RAD23A
Epitope
»Alternatives N-Term
Reactivity
»Alternatives Rabbit, Mouse (Murine), Rat (Rattus), Dog (Canine), Cow (Bovine), Human
Host
»Alternatives Rabbit
Clonality Polyclonal
Conjugate
»Alternatives Un-conjugated
Application
»Alternatives Western Blotting (WB), Immunohistochemistry (IHC)
Pubmed 1 reference available
Catalog no. ABIN310301
Quantity 100 µg
Price
229.00 $   Plus shipping costs $45.00
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Availability Will be delivered in 2 to 3 Business Days
Immunogen The immunogen for anti-RAD23A antibody: synthetic peptide directed towards the N terminal of human RAD23A
Sequence VPSSGSSGREEDAASTLVTGSEYETMLTEIMSMGYERERV VAALRASYNN
Predicted Reactivity Dog : 100%, Guinea pig : 100%, Horse : 100%, Human : 100%, Mouse : 100%, Pig : 100%, Rat : 100%
Characteristics This is a rabbit polyclonal antibody against RAD23A. It was validated on Western Blot and immunohistochemistry. We manufacture rabbit polyclonal antibodies on a large scale of high throughput manner. Our antibodies are peptide based and protein family oriented.
Purification Protein A purified
Alternative Name RAD23A
Background RAD23A is one of two human homologs of Saccharomyces cerevisiae Rad23, a protein involved in nucleotide excision repair (NER). This protein was shown to interact with, and elevate the nucleotide excision activity of 3-methyladenine-DNA glycosylase (MPG), which suggested a role in DNA damage recognition in base excision repair. This protein contains an N-terminal ubiquitin-like domain, which was reported to interact with 26S proteasome, as well as with ubiquitin protein ligase E6AP, and thus suggests that this protein may be involved in the ubiquitin mediated proteolytic pathway in cells.The protein encoded by this gene is one of two human homologs of Saccharomyces cerevisiae Rad23, a protein involved in nucleotide excision repair (NER). This protein was shown to interact with, and elevate the nucleotide excision activity of 3-methyladenine-DNA glycosylase (MPG), which suggested a role in DNA damage recognition in base excision repair. This protein contains an N-terminal ubiquitin-like domain, which was reported to interact with 26S proteasome, as well as with ubiquitin protein ligase E6AP, and thus suggests that this protein may be involved in the ubiquitin mediated proteolytic pathway in cells.
Molecular Weight 40kDa
Gene ID 5886
NCBI Accession NP_005044, NM_005053
UniProt P54725
Restrictions For Research Use only
Format Lyophilized
Reconstitution Add 100 µL of distilled water
Concentration 1mg/mL
Buffer Final anti-RAD23A antibody concentration is 1 mg/mL in PBS buffer.
Handling Advice Avoid repeated freeze-thaw cycles.
Storage -20 °C
Background publications Ju, Xie: "A synthetic defect in protein degradation caused by loss of Ufd4 and Rad23." in: Biochemical and biophysical research communications, Vol. 341, Issue 2, pp. 648-52, 2006 (PubMed).

Alternatives for antigen "RAD23 Homolog A (S. Cerevisiae) (RAD23A)", type "Antibodies"
Hosts (35), (8), (3)
Reactivities (46), (13), (7), (4), (2), (1)
Applications (45), (28), (10), (7), (5), (2), (2), (1), (1)
Conjugates (2), (2), (2)
Epitopes (5), (4), (4), (2), (2), (2), (2), (1), (1), (1)
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