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PPAP2A antibody (N-Term)

PPAP2A Reactivity: Human, Rat, Mouse, Guinea Pig WB, IHC Host: Rabbit Polyclonal unconjugated
Catalog No. ABIN310386
  • Target See all PPAP2A Antibodies
    PPAP2A (Phosphatidic Acid Phosphatase Type 2A (PPAP2A))
    Binding Specificity
    • 3
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    N-Term
    Reactivity
    • 24
    • 8
    • 8
    • 6
    • 4
    • 4
    • 4
    • 3
    • 3
    • 2
    • 2
    • 1
    • 1
    • 1
    Human, Rat, Mouse, Guinea Pig
    Host
    • 23
    • 2
    Rabbit
    Clonality
    • 24
    • 1
    Polyclonal
    Conjugate
    • 18
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This PPAP2A antibody is un-conjugated
    Application
    • 16
    • 7
    • 5
    • 3
    • 1
    • 1
    • 1
    • 1
    • 1
    Western Blotting (WB), Immunohistochemistry (IHC)
    Sequence
    QIYPFQRGFF CKDNSINYPY HDSTVTSTVL ILVGVGLPIS SIILGETLSV
    Predicted Reactivity
    Guinea Pig: 86%, Human: 100%, Mouse: 79%, Rat: 93%
    Characteristics
    This is a rabbit polyclonal antibody against PPAP2A. It was validated on Western Blot and immunohistochemistry.
    Purification
    Protein A purified
    Immunogen
    The immunogen is a synthetic peptide directed towards the N terminal region of human PPAP2A
    Top Product
    Discover our top product PPAP2A Primary Antibody
  • Application Notes
    Optimal working dilutions should be determined experimentally by the investigator.
    Comment

    Antigen size: 285 AA

    Restrictions
    For Research Use only
  • Format
    Liquid
    Concentration
    Lot specific
    Buffer
    Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
    Preservative
    Sodium azide
    Precaution of Use
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Handling Advice
    Avoid repeated freeze-thaw cycles.
    Storage
    -20 °C
    Storage Comment
    For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
  • Evseenko, Latour, Richardson, Corselli, Sahaghian, Cardinal, Zhu, Chan, Dunn, Crooks: "Lysophosphatidic acid mediates myeloid differentiation within the human bone marrow microenvironment." in: PLoS ONE, Vol. 8, Issue 5, pp. e63718, (2013) (PubMed).

  • Target
    PPAP2A (Phosphatidic Acid Phosphatase Type 2A (PPAP2A))
    Alternative Name
    PPAP2A (PPAP2A Products)
    Synonyms
    PPAP2A antibody, wun antibody, LLP1a antibody, LPP1 antibody, PAP-2a antibody, PAP2 antibody, Hic53 antibody, Hpic53 antibody, LPP-1 antibody, mPAP antibody, PAP2A antibody, PAP2a2 antibody, phospholipid phosphatase 1 antibody, phosphatidic acid phosphatase type 2A antibody, phospholipid phosphatase 1 L homeolog antibody, PLPP1 antibody, plpp1 antibody, Ppap2a antibody, plpp1.L antibody, Plpp1 antibody
    Background
    PPAP2A is a member of the phosphatidic acid phosphatase (PAP) family. PAPs convert phosphatidic acid to diacylglycerol, and function in de novo synthesis of glycerolipids as well as in receptor-activated signal transduction mediated by phospholipase D. This protein is an integral membrane glycoprotein, and has been shown to be a surface enzyme that plays an active role in the hydrolysis and uptake of lipids from extracellular space.The protein encoded by this gene is a member of the phosphatidic acid phosphatase (PAP) family. PAPs convert phosphatidic acid to diacylglycerol, and function in de novo synthesis of glycerolipids as well as in receptor-activated signal transduction mediated by phospholipase D. This protein is an integral membrane glycoprotein, and has been shown to be a surface enzyme that plays an active role in the hydrolysis and uptake of lipids from extracellular space. The expression of this gene is found to be regulated by androgen in a prostatic adenocarcinoma cell line. At least two alternatively spliced transcript variants encoding distinct isoforms have been described.
    Alias Symbols: LLP1a, LPP1, PAP-2a, PAP2, PAP2a2, PAP2alpha2, PAPalpha1
    Protein Interaction Partner: FAHD1, IGF2BP2, ILF3, UBC, FXYD1,
    Protein Size: 285
    Molecular Weight
    31 kDa
    Gene ID
    8611
    NCBI Accession
    NM_176895, NP_795714
    Pathways
    Intracellular Steroid Hormone Receptor Signaling Pathway
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