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Details for Product No. ABIN310439

Ring Finger Protein 40, E3 Ubiquitin Protein Ligase (RNF40) (C-Term) antibody

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Antigen
Synonyms BRE1B, RBP95, STARING
Epitope
»Alternatives C-Term
Reactivity
»Alternatives Mouse (Murine), Rat (Rattus), Dog (Canine), Cow (Bovine), Human
Host
»Alternatives Rabbit
Clonality Polyclonal
Conjugate
»Alternatives Un-conjugated
Application
»Alternatives Western Blotting (WB), Immunohistochemistry (IHC)
Pubmed 1 reference available
Catalog no. ABIN310439
Quantity 100 µg
Price
229.00 $   Plus shipping costs $45.00
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Availability Will be delivered in 2 to 3 Business Days
Immunogen The immunogen for anti-RNF40 antibody: synthetic peptide directed towards the C terminal of human RNF40
Sequence KLLREEKDELGEQVLGLKSQVDAQLLTVQKLEEKERALQG SLGGVEKELT
Predicted Reactivity Bovine : 100%, Dog : 100%, Horse : 100%, Human : 100%, Rabbit : 100%
Characteristics This is a rabbit polyclonal antibody against RNF40. It was validated on Western Blot and immunohistochemistry. We manufacture rabbit polyclonal antibodies on a large scale of high throughput manner. Our antibodies are peptide based and protein family oriented.
Purification Protein A purified
Alternative Name RNF40
Background RNF40 contains a RING finger, a motif known to be involved in protein-protein and protein-DNA interactions. This protein was reported to interact with the tumor suppressor protein RB1. Studies of the rat counterpart suggested that this protein may function as an E3 ubiquitin-protein ligase, and facilitate the ubiquitination and degradation of syntaxin 1, which is an essential component of the neurotransmitter release machinery.The protein encoded by this gene contains a RING finger, a motif known to be involved in protein-protein and protein-DNA interactions. This protein was reported to interact with the tumor suppressor protein RB1. Studies of the rat counterpart suggested that this protein may function as an E3 ubiquitin-protein ligase, and facilitate the ubiquitination and degradation of syntaxin 1, which is an essential component of the neurotransmitter release machinery.
Molecular Weight 114kDa
Gene ID 9810
NCBI Accession NP_055586, NM_014771
UniProt O75150
Research Area Proteolysis / Ubiquitin, Ion Channels
Restrictions For Research Use only
Format Lyophilized
Reconstitution Add 100 µL of distilled water
Concentration 1mg/mL
Buffer Final anti-RNF40 antibody concentration is 1 mg/mL in PBS buffer.
Handling Advice Avoid repeated freeze-thaw cycles.
Storage -20 °C
Background publications Zhu, Zheng, Pham et al.: "Monoubiquitination of human histone H2B: the factors involved and their roles in HOX gene regulation." in: Molecular cell, Vol. 20, Issue 4, pp. 601-11, 2005 (PubMed).

Alternatives for antigen "Ring Finger Protein 40, E3 Ubiquitin Protein Ligase (RNF40)", type "Antibodies"
Hosts (37), (3)
Reactivities (39), (14), (14), (12), (12), (12)
Applications (30), (15), (10), (9), (6), (5), (2), (1), (1)
Conjugates (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1)
Epitopes (4), (2), (2), (2), (1), (1), (1), (1), (1), (1)
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