Ribophorin II antibody (N-Term)

Catalog No. ABIN310678

Product Details anti-Ribophorin II Antibody

Target: Ribophorin II (RPN2)

Binding Specificity: N-Term

Reactivity: Human, Mouse, Rat, Dog, Horse, Cow, Pig, Rabbit

Host: Rabbit

Clonality: Polyclonal

Conjugate: This Ribophorin II antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (IHC)

Sequence: ASQEALSALT ARLSKEETVL ATVQALQTAS HLSQQADLRS IVEEIEDLVA

Predicted Reactivity: Cow: 93%, Dog: 100%, Horse: 100%, Human: 100%, Mouse: 100%, Pig: 93%, Rabbit: 100%, Rat: 100%

Characteristics: This is a rabbit polyclonal antibody against RPN2. It was validated on Western Blot and immunohistochemistry.

Purification: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the N terminal region of human RPN2

Application Details

Application Notes: Optimal working dilutions should be determined experimentally by the investigator.

Comment:

Antigen size: 631 AA

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freeze-thaw cycles.

Storage: -20 °C

Storage Comment: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

References for anti-Ribophorin II antibody (ABIN310678)

Fujimoto, Goi, Hirono: "Expression of ribophorine II is a promising prognostic factor in human gastric adenocarcinoma." in: International journal of oncology, Vol. 50, Issue 2, pp. 448-456, (2016) (PubMed).

Target Details for Ribophorin II

Target: Ribophorin II (RPN2)

Alternative Name: RPN2 (RPN2 Products)

Synonyms: RIBIIR antibody, RPN-II antibody, RPNII antibody, SWP1 antibody, RPN2 antibody, 1300012C06Rik antibody, AV261018 antibody, Rpn-2 antibody, fb95d11 antibody, fj62b10 antibody, wu:fb61f08 antibody, wu:fb74e07 antibody, wu:fb95d11 antibody, wu:fj41f11 antibody, wu:fj62b10 antibody, rpn2 antibody, ribophorin II antibody, dolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit 2 antibody, ribophorin II S homeolog antibody, RPN2 antibody, Rpn2 antibody, rpn2 antibody, LOC5579328 antibody, Bm1_30625 antibody, rpn2.S antibody

Background: RPN2 is a type I integral membrane protein found only in the rough endoplasmic reticulum. The protein is part of an N-oligosaccharyl transferase complex that links high mannose oligosaccharides to asparagine residues found in the Asn-X-Ser/Thr consensus motif of nascent polypeptide chains.This gene encodes a type I integral membrane protein found only in the rough endoplasmic reticulum. The encoded protein is part of an N-oligosaccharyl transferase complex that links high mannose oligosaccharides to asparagine residues found in the Asn-X-Ser/Thr consensus motif of nascent polypeptide chains. This protein is similar in sequence to the yeast oligosaccharyl transferase subunit SWP1.
Alias Symbols: RIBIIR, RPN-II, RPNII, SWP1
Protein Interaction Partner: UBC, FUS, FAF1, VAPB, EED, ADRB2, CLN3, MMS19, RCHY1, UBL4A, ESR1, RHOA, RPN1, ILF3, PDIA3, CANX, ATP5A1, STT3B, TM9SF2, FBXO6, CUL3, FBXO25, SIRT7, TCF3, AUP1, ARRB2, NDRG1, SUMO2, FBN3, RBBP4, NGFR, HDAC5, MYC, RNF185, H2AFX, BRE, ADRM1, EZH2, GSTK1, TM
Protein Size: 631

Molecular Weight: 69 kDa

Gene ID: 6185

NCBI Accession: NM_002951, NP_002942

UniProt: P04844