ECHS1 antibody (Middle Region)

Catalog No. ABIN310715

Product Details anti-ECHS1 Antibody

Target: ECHS1 (Enoyl CoA Hydratase, Short Chain, 1, Mitochondrial (ECHS1))

Binding Specificity: Middle Region

Reactivity: Human, Mouse, Rat, Dog, Rabbit, Cow, Zebrafish (Danio rerio), Guinea Pig, Horse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This ECHS1 antibody is un-conjugated

Application: Western Blotting (WB)

Sequence: RAVGKSLAME MVLTGDRISA QDAKQAGLVS KICPVETLVE EAIQCAEKIA

Predicted Reactivity: Cow: 100%, Dog: 100%, Guinea Pig: 93%, Horse: 100%, Human: 100%, Mouse: 100%, Rabbit: 93%, Rat: 100%, Zebrafish: 86%

Characteristics: This is a rabbit polyclonal antibody against ECHS1. It was validated on Western Blot using a cell lysate as a positive control.

Purification: Protein A purified

Immunogen: The immunogen is a synthetic peptide directed towards the middle region of human ECHS1

Application Details

Application Notes: Optimal working dilutions should be determined experimentally by the investigator.

Comment:

Antigen size: 290 AA

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freeze-thaw cycles.

Storage: -20 °C

Storage Comment: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Target Details for ECHS1

Target: ECHS1 (Enoyl CoA Hydratase, Short Chain, 1, Mitochondrial (ECHS1))

Alternative Name: ECHS1 (ECHS1 Products)

Synonyms: SCEH antibody, cOR6not antibody, fj55e05 antibody, si:zc217g15.1 antibody, wu:fj55e05 antibody, C80529 antibody, enoyl-CoA hydratase, short chain, 1, mitochondrial L homeolog antibody, enoyl-CoA hydratase, short chain 1 antibody, enoyl CoA hydratase, short chain, 1, mitochondrial antibody, enoyl Coenzyme A hydratase, short chain, 1, mitochondrial antibody, echs1.L antibody, ECHS1 antibody, Echs1 antibody, echs1 antibody

Background: ECHS1 functions in the second step of the mitochondrial fatty acid beta-oxidation pathway. It catalyzes the hydration of 2-trans-enoyl-coenzyme A (CoA) intermediates to L-3-hydroxyacyl-CoAs. ECHS1 is a member of the hydratase/isomerase superfamily. It localizes to the mitochondrial matrix.The protein encoded by this gene functions in the second step of the mitochondrial fatty acid beta-oxidation pathway. It catalyzes the hydration of 2-trans-enoyl-coenzyme A (CoA) intermediates to L-3-hydroxyacyl-CoAs. The gene product is a member of the hydratase/isomerase superfamily. It localizes to the mitochondrial matrix. Transcript variants utilizing alternative transcription initiation sites have been described in the literature.
Alias Symbols: SCEH
Protein Interaction Partner: SUMO2, UBC, MDM2, GINS3, SMEK2, CNDP2, DCPS, ABHD14A, YWHAQ, SLC9A3R1, USP14, YWHAZ, VCL, UBE2V1, TGM2, RAP1GDS1, PFAS, HSPA9, GSS, CAPN1, CLDN12, UBA1, PPM1B, SERPINA1, ECHS1, CYP2E1, GRB2, UCHL5, UBA5, DDA1, CBWD2, EPB41,
Protein Size: 290

Molecular Weight: 28 kDa

Gene ID: 1892

NCBI Accession: NM_004092, NP_004083

UniProt: P30084

Pathways: Monocarboxylic Acid Catabolic Process