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Details for Product No. ABIN310757

Centromere Protein A (CENPA) (N-Term) antibody

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Antigen
Synonyms
CENP-A, CenH3, Cenp-A, RGD1563607, BcDNA:RE21270, CENP-A/CID, CENP-A/Cid, CENP-C, CENPA, CG13329, CID, CID/CENP-A, CenH3/CID, CenH3[CID], CenH3[Cid], CenpA, CenpA/CID, Cid, Cid[Mel], Dmel\\CG13329, ce ... show more
Epitope
»Alternatives N-Term
Reactivity
»Alternatives Human
Host
»Alternatives Rabbit
Clonality Polyclonal
Conjugate
»Alternatives Un-conjugated
Application
»Alternatives Western Blotting (WB), Immunohistochemistry (IHC)
Pubmed 1 reference available
Catalog no. ABIN310757
Quantity 100 µg
Price
229.00 $   Plus shipping costs $45.00
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Availability Will be delivered in 2 to 3 Business Days
Immunogen The immunogen for anti-CENPA antibody: synthetic peptide directed towards the N terminal of human CENPA
Sequence MGPRRRSRKPEAPRRRSPSPTPTPGPSRRGPSLGASSHQH SRRRQGWLKE
Predicted Reactivity Human : 100%
Characteristics This is a rabbit polyclonal antibody against CENPA. It was validated on Western Blot and immunohistochemistry. We manufacture rabbit polyclonal antibodies on a large scale of high throughput manner. Our antibodies are peptide based and protein family oriented.
Purification Protein A purified
Alternative Name CENPA
Background Centromeres are the differentiated chromosomal domains that specify the mitotic behavior of chromosomes. CENPA is a centromere protein which contains a histone H3 related histone fold domain that is required for targeting to the centromere. CENPA is proposed to be a component of a modified nucleosome or nucleosome-like structure in which it replaces 1 or both copies of conventional histone H3 in the (H3-H4)2 tetrameric core of the nucleosome particle.Centromeres are the differentiated chromosomal domains that specify the mitotic behavior of chromosomes. CENPA encodes a centromere protein which contains a histone H3 related histone fold domain that is required for targeting to the centromere. CENPA is proposed to be a component of a modified nucleosome or nucleosome-like structure in which it replaces 1 or both copies of conventional histone H3 in the (H3-H4)2 tetrameric core of the nucleosome particle.
Molecular Weight 16kDa
Gene ID 1058
NCBI Accession NP_001800, NM_001809
UniProt P49450
Research Area Chromatin and Nuclear Signaling, Cell Cycle
Restrictions For Research Use only
Format Lyophilized
Reconstitution Add 100 µL of distilled water
Concentration 1mg/mL
Buffer Final anti-CENPA antibody concentration is 1 mg/mL in PBS buffer.
Handling Advice Avoid repeated freeze-thaw cycles.
Storage -20 °C
Background publications Black, Foltz, Chakravarthy et al.: "Structural determinants for generating centromeric chromatin." in: Nature, Vol. 430, Issue 6999, pp. 578-82, 2004 (PubMed).

Alternatives for antigen "Centromere Protein A (CENPA)", type "Antibodies"
Hosts (57), (11), (3)
Reactivities (66), (14), (14), (13), (12), (12), (2), (1)
Applications (40), (29), (20), (14), (13), (7), (5), (4), (2), (1)
Conjugates (2), (2), (2), (2), (2), (2), (2), (2), (2), (2), (2)
Epitopes (18), (13), (3), (3), (3), (2), (2), (2), (1), (1), (1), (1)
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