ASF1B antibody (Middle Region)

Catalog No. ABIN310800

Product Details anti-ASF1B Antibody

Target: ASF1B (ASF1 Anti-Silencing Function 1 Homolog B (ASF1B))

Binding Specificity: Middle Region

Reactivity: Human, Mouse, Rat, Dog, Cow, Guinea Pig, Horse, Rabbit, Sheep, Zebrafish (Danio rerio)

Host: Rabbit

Clonality: Polyclonal

Conjugate: This ASF1B antibody is un-conjugated

Application: Western Blotting (WB)

Sequence: YHGQEFIRVG YYVNNEYLNP ELRENPPMKP DFSQLQRNIL ASNPRVTRFH

Predicted Reactivity: Cow: 100%, Dog: 100%, Guinea Pig: 100%, Horse: 93%, Human: 100%, Mouse: 100%, Rabbit: 93%, Rat: 100%, Sheep: 93%, Zebrafish: 86%

Characteristics: This is a rabbit polyclonal antibody against ASF1B. It was validated on Western Blot using a cell lysate as a positive control.

Purification: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the middle region of human ASF1B

Application Details

Application Notes: Optimal working dilutions should be determined experimentally by the investigator.

Comment:

Antigen size: 202 AA

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freeze-thaw cycles.

Storage: -20 °C

Storage Comment: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Target Details for ASF1B

Target: ASF1B (ASF1 Anti-Silencing Function 1 Homolog B (ASF1B))

Alternative Name: ASF1B (ASF1B Products)

Synonyms: CIA-II antibody, asf1-b antibody, asf1a antibody, asf1a-b antibody, asf1ab antibody, cia-ii antibody, 1700003K02Rik antibody, AA409591 antibody, asf1b antibody, fc68a10 antibody, wu:fc68a10 antibody, zgc:77178 antibody, ASF1B antibody, F16F17.110 antibody, F16F17_110 antibody, SGA01 antibody, SGA1 antibody, anti- silencing function 1b antibody, asf1 antibody, MGC89345 antibody, asb1bb antibody, wu:fb20g03 antibody, zgc:76977 antibody, anti-silencing function 1B histone chaperone antibody, anti-silencing function 1B histone chaperone L homeolog antibody, anti-silencing function 1Ba histone chaperone antibody, anti- silencing function 1b antibody, histone chaperone ASF1B antibody, anti-silencing function 1Bb histone chaperone antibody, ASF1B antibody, asf1b.L antibody, Asf1b antibody, asf1ba antibody, LOC9304878 antibody, asf1b antibody, asf1bb antibody

Background: ASF1B is a member of the H3/H4 family of histone chaperone proteins and is similar to the anti-silencing function-1 gene in yeast. The encoded protein is the substrate of the tousled-like kinase family of cell cycle-regulated kinases, and may play a key role in modulating the nucleosome structure of chromatin by ensuring a constant supply of histones at sites of nucleosome assembly.This gene encodes a member of the H3/H4 family of histone chaperone proteins and is similar to the anti-silencing function-1 gene in yeast. The encoded protein is the substrate of the tousled-like kinase family of cell cycle-regulated kinases, and may play a key role in modulating the nucleosome structure of chromatin by ensuring a constant supply of histones at sites of nucleosome assembly.
Alias Symbols: CIA-II, FLJ10604
Protein Interaction Partner: UBC, HIST3H3, H3F3A, MMS22L, TONSL, MCM6, HIST4H4, HIST1H3A, KHSRP, IDH1, CDAN1, IPO4, ASF1A, HIST1H3C, TLK2, HIST1H3E, MCM2, HAT1, RBBP7, CHAF1B, HIRA, UL30, UL52, HCFC1, C15orf41, TLK1, HIST1H4F, HIST1H3B, CHAF1A, H3F3B, TAF1, MRPS7, UBXN1, DOK2, HIST1H
Protein Size: 202

Molecular Weight: 22 kDa

Gene ID: 55723

NCBI Accession: NM_018154, NP_060624

UniProt: Q9NVP2

Pathways: Regulation of Cell Size