NDRG Family Member 2 (NDRG2) (C-Term) antibody

Details for Product No. ABIN310960
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Antigen
Synonyms NDRG2, AI182517, AU040374, Ndr2, SYLD, im:6909381, si:dkey-88n24.1, zgc:101847
Epitope
C-Term
(9), (8), (8), (8), (3), (3), (2), (2), (1)
Reactivity
Mouse (Murine), Rat (Rattus), Xenopus laevis, Cow (Bovine), Pig (Porcine), Dog (Canine), Human
(52), (26), (23), (13), (12), (12)
Host
Rabbit
(41), (14), (3)
Clonality
Polyclonal
Conjugate
Un-conjugated
(3), (3), (3), (2), (2), (2), (1), (1), (1), (1), (1), (1), (1), (1)
Application
Immunohistochemistry (IHC), Western Blotting (WB)
(47), (26), (10), (9), (5), (3), (2), (1)
Pubmed 1 reference available
Quantity 50 μg
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Catalog No. ABIN310960
289.00 $
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Immunogen Synthetic peptide directed towards the C terminal of human NDRG2
Sequence GYMASSCMTR LSRSRTASLT SAASVDGNRS RSRTLSQSSE SGTLSSGPPG
Predicted Reactivity African clawed frog : 100 %, Bovine : 100 %, Human : 100 %, Mouse : 100 %, Pig : 100 %, Rabbit : 100 %, Rat : 100 %, Dog : 90 %, Guinea pig : 90 %
Characteristics This is a rabbit polyclonal antibody against NDRG2. It was validated on Western Blot using a cell lysate as a positive control.
Purification Affinity Purified
Alternative Name NDRG2
Background NDRG2��s gene is a member of the N-myc downregulated gene family which belongs to the alpha/beta hydrolase superfamily. NDRG2 is a cytoplasmic protein that may play a role in neurite outgrowth. Its gene may be involved in glioblastoma carcinogenesis.This gene is a member of the N-myc downregulated gene family which belongs to the alpha/beta hydrolase superfamily. The protein encoded by this gene is a cytoplasmic protein that may play a role in neurite outgrowth. This gene may be involved in glioblastoma carcinogenesis. Several alternatively spliced transcript variants of this gene have been described, but the full-length nature of some of these variants has not been determined.
Molecular Weight 39 kDa
Gene ID 57447
NCBI Accession NP_057334, NM_016250
UniProt Q9UN36
Research Area Cancer, Alzheimer's Disease
Application Notes Optimal working dilutions should be determined experimentally by the investigator.
Comment

Antigen size: 357 AA

Restrictions For Research Use only
Format Lyophilized
Reconstitution Add 50 µL of distilled water.
Concentration 1 mg/mL
Buffer PBS buffer with 2 % sucrose
Handling Advice Avoid repeated freeze-thaw cycles.
Storage -20 °C
Storage Comment For longer periods of storage, store at -20 °C
Supplier Images
anti-NDRG Family Member 2 (NDRG2) (C-Term) antibody WB Suggested Anti-NDRG2 Antibody Titration: 0.2-1 ug/ml
Positive Control: HepG2 cell lysate
anti-NDRG Family Member 2 (NDRG2) (C-Term) antibody (2) anti-NDRG Family Member 2 (NDRG2) (C-Term) antibody (Image 2)
Background publications Lusis, Watson, Chicoine et al.: "Integrative genomic analysis identifies NDRG2 as a candidate tumor suppressor gene frequently inactivated in clinically aggressive meningioma." in: Cancer research, Vol. 65, Issue 16, pp. 7121-6, 2005 (PubMed).

Validation Images
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