OAT (C-Term) antibody

Details for Product No. ABIN310979
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Antigen
Epitope
C-Term
(9), (8), (4), (2), (1), (1), (1), (1), (1)
Reactivity
Mouse (Murine), Rat (Rattus), Xenopus laevis, Cow (Bovine), Pig (Porcine), Human, Chicken
(35), (13), (11), (1), (1), (1), (1), (1)
Host
Rabbit
(24), (9)
Clonality
Polyclonal
Conjugate
Un-conjugated
(1), (1), (1), (1), (1), (1)
Application
Immunohistochemistry (IHC), Western Blotting (WB)
(31), (19), (11), (5), (4), (3), (3), (1)
Pubmed 1 reference available
Quantity 100 µg
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Catalog No. ABIN310979
229.00 $
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Immunogen Synthetic peptide directed towards the C terminal of human OAT
Sequence VRGKGLLNAI VIKETKDWDA WKVCLRLRDN GLLAKPTHGD IIRFAPPLVI
Predicted Reactivity African clawed frog : 100 %, Bovine : 100 %, Chicken : 100 %, Dog : 100 %, Horse : 100 %, Human : 100 %, Mouse : 100 %, Pig : 100 %, Rat : 100 %
Characteristics This is a rabbit polyclonal antibody against OAT. It was validated on Western Blot using a cell lysate as a positive control.
Purification Protein A purified
Background OAT is a key enzyme in the pathway that converts arginine and ornithine into the major excitatory and inhibitory neurotransmitters glutamate and GABA. Mutations of this enzyme cause the autosomal recessive eye disease Gyrate Atrophy.This gene encodes the mitochondrial enzyme ornithine aminotransferase, which is a key enzyme is the pathway that converts arginine and ornithine into the major excitatory and inhibitory neurotransmitters glutamate and GABA. Mutations that result in a deficiency of this enzyme cause the autosomal recessive eye disease Gyrate Atrophy.
Molecular Weight 45 kDa
Gene ID 4942
NCBI Accession NM_000274, NP_000265
UniProt P04181
Application Notes Optimal working dilutions should be determined experimentally by the investigator.
Comment

Antigen size: 439 AA

Restrictions For Research Use only
Format Lyophilized
Reconstitution Add 100 µL of distilled water.
Concentration 1 mg/mL
Buffer PBS buffer with 2 % sucrose
Handling Advice Avoid repeated freeze-thaw cycles.
Storage -20 °C
Storage Comment For longer periods of storage, store at -20 °C
Supplier Images
anti-OAT (C-Term) antibody WB Suggested Anti-OAT Antibody Titration: 5.0ug/ml
Positive Control: HepG2 cell lysate
Product cited in: Ewing, Chu, Elisma et al.: "Large-scale mapping of human protein-protein interactions by mass spectrometry. ..." in: Molecular systems biology, Vol. 3, pp. 89, 2007 (PubMed).

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