Mitogen-Activated Protein Kinase Kinase Kinase 1 (MAP3K1) (C-Term) antibody

Details for Product No. ABIN311064
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Antigen
Synonyms MAP3K1, Mekk1, MAPKKK1, MEKK1, Mekk, ARAKIN, ATMEKK1, MAPK/ERK kinase kinase 1, MAPKKK8, T15F16.5, T15F16_5, MEKK, MEKK 1, SRXY6
Epitope
C-Term
(19), (11), (10), (6), (4), (3), (3), (2), (2), (1), (1), (1), (1), (1), (1), (1), (1), (1)
Reactivity
Rabbit, Mouse (Murine), Rat (Rattus), Cow (Bovine), Human
(54), (27), (19)
Host
Rabbit
(60), (3)
Clonality
Polyclonal
Conjugate
Un-conjugated
(3), (3), (3), (2), (2), (2)
Application
Western Blotting (WB)
(46), (44), (18), (10), (10), (4), (2), (2), (1), (1)
Pubmed 1 reference available
Quantity 50 µg
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Catalog No. ABIN311064
289.00 $
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Immunogen Synthetic peptide directed towards the C terminal of human MAP3K1
Sequence LGAFSSCYQA QDVGTGTLMA VKQVTYVRNT SSEQEEVVEA LREEIRMMSH
Predicted Reactivity Bovine : 100 %, Chicken : 100 %, Dog : 100 %, Guinea pig : 100 %, Horse : 100 %, Mouse : 100 %, Pig : 100 %, Rabbit : 100 %, Rat : 100 %
Characteristics This is a rabbit polyclonal antibody against MAP3K1. It was validated on Western Blot using a cell lysate as a positive control.
Purification Affinity Purified
Alternative Name MAP3K1
Background MAP3K, or MEK kinase, is a serine/threonine kinase that occupies a pivotal role in a network of phosphorylating enzymes integrating cellular responses to a number of mitogenic and metabolic stimuli, including insulin (MIM 176730) and many growth factors.MAP3K, or MEK kinase, is a serine/threonine kinase that occupies a pivotal role in a network of phosphorylating enzymes integrating cellular responses to a number of mitogenic and metabolic stimuli, including insulin (MIM 176730) and many growth factors.
Molecular Weight 164 kDa
Gene ID 4214
NCBI Accession NP_005912, NM_005921
UniProt Q13233
Research Area Kinases/Phosphatases
Application Notes Optimal working dilutions should be determined experimentally by the investigator.
Comment

Antigen size: 1512 AA

Restrictions For Research Use only
Format Lyophilized
Reconstitution Add 50 µL of distilled water.
Concentration 1 mg/mL
Buffer PBS buffer with 2 % sucrose
Handling Advice Avoid repeated freeze-thaw cycles.
Storage -20 °C
Storage Comment For longer periods of storage, store at -20 °C
Supplier Images
anti-Mitogen-Activated Protein Kinase Kinase Kinase 1 (MAP3K1) (C-Term) antibody WB Suggested Anti-MAP3K1 Antibody Titration: 0.2-1 ug/ml
Positive Control: 721_B cell lysate
General Hancock, Beckly, Geremia et al.: "Clinical and molecular characteristics of isolated colonic Crohn's disease." in: Inflammatory bowel diseases, Vol. 14, Issue 12, pp. 1667-77, 2008 (PubMed).

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