PGS1 antibody (C-Term)

Catalog No. ABIN311099

Product Details anti-PGS1 Antibody

Target: PGS1 (Phosphatidylglycerophosphate Synthase 1 (PGS1))

Binding Specificity: C-Term

Reactivity: Human, Mouse, Rat, Cow, Guinea Pig, Dog, Horse, Rabbit, Zebrafish (Danio rerio)

Host: Rabbit

Clonality: Polyclonal

Conjugate: This PGS1 antibody is un-conjugated

Application: Western Blotting (WB)

Sequence: RVQLQEYWRR GWTFHAKGLW LYLAGSSLPC LTLIGSPNFG YRSVHRDLEA

Predicted Reactivity: Cow: 100%, Dog: 100%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 100%, Rabbit: 100%, Rat: 100%, Zebrafish: 100%

Characteristics: This is a rabbit polyclonal antibody against PGS1. It was validated on Western Blot using a cell lysate as a positive control.

Purification: Protein A purified

Immunogen: The immunogen is a synthetic peptide directed towards the C terminal region of human PGS1

Application Details

Application Notes: Optimal working dilutions should be determined experimentally by the investigator.

Comment:

Antigen size: 549 AA

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freeze-thaw cycles.

Storage: -20 °C

Storage Comment: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

References for anti-PGS1 antibody (ABIN311099)

Croston, Shepherd, Thapa, Nichols, Lewis, Dabkowski, Jagannathan, Baseler, Hollander: "Evaluation of the cardiolipin biosynthetic pathway and its interactions in the diabetic heart." in: Life sciences, Vol. 93, Issue 8, pp. 313-22, (2013) (PubMed).

Kiebish, Yang, Sims, Jenkins, Liu, Mancuso, Zhao, Guan, Abendschein, Han, Gross: "Myocardial regulation of lipidomic flux by cardiolipin synthase: setting the beat for bioenergetic efficiency." in: The Journal of biological chemistry, Vol. 287, Issue 30, pp. 25086-97, (2012) (PubMed).

Target Details for PGS1

Target: PGS1 (Phosphatidylglycerophosphate Synthase 1 (PGS1))

Alternative Name: PGS1 (PGS1 Products)

Synonyms: 2610019F11Rik antibody, 4933424M23Rik antibody, SAF antibody, RGD1305052 antibody, phosphatidylglycerophosphate synthase 1 antibody, phosphatidylglycerophosphate synthase 1 S homeolog antibody, PGS1 antibody, Pgs1 antibody, pgs1.S antibody, pgs1 antibody

Background: PGS1 functions in the biosynthesis of the anionic phospholipids phosphatidylglycerol and cardiolipin.
Alias Symbols: DKFZP762M186, MGC131960
Protein Interaction Partner: UBC, PDLIM1, GABARAP,
Protein Size: 549

Molecular Weight: 60 kDa

Gene ID: 9489

NCBI Accession: NM_024419

UniProt: Q32NB8