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Details for Product No. ABIN311312

Inhibitor of Growth Family, Member 1 (ING1) (C-Term) antibody

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Antigen
Synonyms p33, p47, p33ING1, p24ING1c, p33ING1b, p47ING1a, p33ING1c, 2610028J21Rik, AA407184, AI875420, mING1h, p33Ing1, p37Ing1b, ING1, si:busm1-40g1.1, si:dz40g1.1, wu:fc94a02, zgc:100910, xing1, zgc:136918
Epitope
»Alternatives C-Term
Reactivity
»Alternatives Mouse (Murine), Rat (Rattus), Xenopus laevis, Cow (Bovine), Dog (Canine), Zebrafish (Danio rerio), Human
Host
»Alternatives Rabbit
Clonality Polyclonal
Conjugate
»Alternatives Un-conjugated
Application
»Alternatives Western Blotting (WB)
Pubmed 1 reference available
Catalog no. ABIN311312
Quantity 100 µg
Price
229.00 $   Plus shipping costs $45.00
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Availability Will be delivered in 2 to 3 Business Days
Immunogen The immunogen for anti-ING1 antibody: synthetic peptide directed towards the C terminal of human ING1
Sequence EKKAKTSKKKKRSKAKAEREASPADLPIDPNEPTYCLCNQ VSYGEMIGCD
Predicted Reactivity African clawed frog : 100%, Bovine : 100%, Dog : 100%, Guinea pig : 100%, Human : 100%, Mouse : 100%, Pig : 100%, Rat : 100%, Chicken : 92%, Horse : 92%, Rabbit : 92%, Zebrafish : 85%
Characteristics This is a rabbit polyclonal antibody against ING1. It was validated on Western Blot using a cell lysate as a positive control. We strive to provide antibodies covering each member of a whole protein family of your interest.
Purification Protein A purified
Alternative Name ING1
Background ING1 is a tumor suppressor protein that can induce cell growth arrest and apoptosis. The protein is a nuclear protein that physically interacts with the tumor suppressor protein TP53 and is a component of the p53 signaling pathway. Reduced expression and rearrangement of ING1 gene have been detected in various cancers.This gene encodes a tumor suppressor protein that can induce cell growth arrest and apoptosis. The encoded protein is a nuclear protein that physically interacts with the tumor suppressor protein TP53 and is a component of the p53 signaling pathway. Reduced expression and rearrangement of this gene have been detected in various cancers. Multiple alternatively spliced transcript variants encoding distinct isoforms have been reported.
Molecular Weight 32kDa
Gene ID 3621
NCBI Accession NP_937862, NM_198219
UniProt Q5T9H0
Research Area Cancer, Transcription Factors, Apoptosis/Necrosis
Restrictions For Research Use only
Format Lyophilized
Reconstitution Add 100 µL of distilled water
Concentration 1mg/mL
Buffer Final anti-ING1 antibody concentration is 1 mg/mL in PBS buffer.
Handling Advice Avoid repeated freeze-thaw cycles.
Storage -20 °C
Background publications Ahmed, Kelly, Anderson et al.: "The predictive value of p53 and p33(ING1b) in patients with Dukes'C colorectal cancer." in: Colorectal disease : the official journal of the Association of Coloproctology of Great Britain and Ireland, Vol. 10, Issue 4, pp. 344-51, 2008 (PubMed).

Alternatives for antigen "Inhibitor of Growth Family, Member 1 (ING1)", type "Antibodies"
Hosts (33), (19), (9)
Reactivities (56), (26), (17)
Applications (48), (37), (10), (10), (7), (4), (4), (3), (3), (1), (1)
Conjugates (3), (2), (1), (1), (1), (1), (1), (1), (1), (1), (1)
Epitopes (13), (11), (6), (3), (3), (2), (1), (1)
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